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NIKOO Chemical - Skincare Raw Material Supply and Custom Solution Specialist for 15 years. 

Innovative Applications and Market Opportunities of Liposome Technology in Cosmetics

The cosmetics liposome market is expanding at an annual growth rate of 38%, with the market size expected to exceed 8 billion yuan by 2024. This growth is driven by consumers' dual demand for “highly effective ingredients + gentle experience” and the mature implementation of nanotechnology delivery systems.

 

Three Core Technological Breakthroughs

 

1. Multi-Layer Liposomes (MLV): Formed using thin-film dispersion technology to create 3–10 layers of phospholipid bilayers, enabling gradient loading of multiple components (e.g., anti-inflammatory factors on the outer layer and repairing ingredients on the inner layer), suitable for complex functional products;

 

2. Immune Liposomes (IL): Modifying the surface of liposomes with targeted peptide segments (such as EGF receptor antibodies) enables active ingredients to concentrate in specific skin cells (such as fibroblasts), with experiments showing a 5-fold increase in active ingredient utilisation;

 

3. Solid lipid nanoparticles (SLN): Replacing part of the phospholipids with plant wax improves thermal stability (melting point up to 55°C), addressing the issue of traditional liposomes breaking down at high temperatures during storage, making them suitable for skincare formulations in tropical regions.

 

Differentiated product development directions

 

- Anti-pollution protection: Encapsulating fullerene within liposomes forms a ‘free radical capture barrier,’ neutralising 92% of urban PM2.5-bound pollutants, suitable for a dedicated skincare series for urban populations;

 

- Scalp anti-ageing: Liposome-encapsulated hair follicle activating peptides (such as Capixyl™ analogues) penetrate into dermal papilla cells, increasing hair follicle stem cell activity by 35%. Clinical trials over three months showed a 28% increase in new hair density;

 

- Makeup and skincare integration: Adding hyaluronic acid liposomes to foundation liquid provides 24-hour continuous moisturisation while applying makeup. Tests show a 41% increase in skin moisture content compared to traditional foundation.

 

Compliance and industrialisation capabilities

Our liposome raw materials comply with international regulations such as the EU CPNP and US FDA. Biocompatibility testing (ISO 10993-5) shows a cell survival rate of over 95%. Scalable production employs microjet homogenisation technology, with a single batch capacity of 1,000 L and particle size uniformity controlled within ±10 nm. From concept design to mass production, we provide comprehensive technical support covering ‘ingredient screening, loading optimisation, and stability testing.’

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