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NIKOO Chemical - Skincare Raw Material Supply and Custom Solution Specialist for 15 years. 

Skin free radical killer | Recombinant humanized metallothionein

Skin free radical killer | Recombinant humanized metallothionein 1

Metallothionein is a low molecular weight protein with metal binding ability and high induction properties. It is a short peptide rich in cysteine ​​and has a high affinity for a variety of heavy metals. It is a protein with low molecular weight, extremely high cysteine ​​residues and metal content. The metals bound to it are mainly cadmium, copper and zinc, which are widely present in various organisms from microorganisms to humans, and its structure is highly conserved.

 

The important physiological function of MT is that it is the most effective free radical scavenger known so far. Its ability to scavenge free radicals (·OH) is about several thousand times that of SOD, and its ability to scavenge oxygen free radicals (·O) is about 25 times that of glutathione (GSH), and it has strong antioxidant activity.

 

Due to the special chemical structure of MT, the metal in it is kinetically unstable and the thiol group has a nucleophilic tendency, which makes MT easy to interact with certain electrophilic substances, especially with certain free radicals.

Skin free radical killer | Recombinant humanized metallothionein 2

Metallothionein (MT): The "new favorite" in the cosmetics industry

Metallothionein (MT) is a biologically active protein extracted from animals. It is rich in amino acids and cysteine and can bind to a variety of metal ions. It has powerful beauty effects and has become a new favorite in the cosmetics field.

Skin free radical killer | Recombinant humanized metallothionein 3

MT's beauty effects: "Guardian of Appearance" for Workers

1. Anti-oxidation, anti-aging

Workers often face huge pressure and irregular life, free radicals accumulate in the body, accelerating skin aging. MT is a "superhero" in the antioxidant world. Its antioxidant capacity is thousands of times that of superoxide dismutase (SOD). It can effectively remove free radicals, delay skin aging, and keep you young and energetic in the workplace.

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2. Supplement trace elements and promote skin health MT is rich in trace elements such as zinc, iron, and copper, which are essential for skin health. By supplementing MT, you can promote the metabolism of skin cells, improve the skin's nutritional supply and metabolic function, and make your skin healthier and more lustrous.

 

3. Repair damaged cells and enhance skin immunity MT can not only remove free radicals, but also repair damaged skin cells and enhance skin immunity. For common skin problems of working people, such as allergies, dermatitis, sunburn, etc., MT can play a significant repair role. It can also prevent ultraviolet damage to the skin and reduce the risk of sunburn and skin cancer.
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Skin free radical killer | Recombinant humanized metallothionein 6
4. Improve skin dryness and enhance skin elasticity MT can promote the metabolism of skin cells, increase the skin's ability to retain moisture, and improve problems such as dry and rough skin. It can also stimulate the synthesis of collagen, enhance skin elasticity and firmness, and keep your skin moisturized and smooth even during high-intensity work.

 

MT and SOD: Who is the real "king of antioxidants"?

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Compared with the traditional antioxidant SOD, MT has the following significant advantages:

1. Stronger free radical scavenging ability: MT can not only scavenge superoxide anions (.O2), but also scavenge hydroxyl radicals (.OH), while SOD can only scavenge the former. This means that MT is more comprehensive and powerful in anti-oxidation.

2. Longer half-life: MT has a half-life of up to 2 years, while SOD has a half-life of only 60 seconds. This means that MT can work longer in the skin.

3. Higher stability: MT can remain active when heated at 85°C for 10 minutes, while SOD will be inactivated at 60°C. This makes MT more suitable for use in cosmetics and skin care products. Better absorbability: MT has a molecular weight of only about 6000, which is easier to be absorbed by the skin than SOD, and can work more efficiently.

4. Stronger radiation resistance: MT's resistance to ionizing radiation is much higher than SOD, and can effectively prevent ultraviolet damage to the skin.

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MT cosmetics: the future trend of beauty and skin care

 

With people's pursuit of health and natural products, MT cosmetics are becoming a popular choice in the field of beauty and skin care. It can not only beautify the skin, but also prevent and treat a variety of skin problems. At present, the United States, Japan and other countries have launched cosmetics and drugs containing MT, which can not only protect the skin from heavy metals and ultraviolet rays, but also improve the overall health of the skin.

 

In China, the research on MT has also received great attention from the government and has been included in many national scientific research projects. With the deepening of research and the advancement of technology, MT cosmetics will surely be more widely used in the field of beauty and skin care.

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