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3-O-Ethyl Ascorbyl Ether: Advanced Stabilized Vitamin C for Skin Brightening & Anti-Aging 1
3-O-Ethyl Ascorbyl Ether: Advanced Stabilized Vitamin C for Skin Brightening & Anti-Aging 2
3-O-Ethyl Ascorbyl Ether: Advanced Stabilized Vitamin C for Skin Brightening & Anti-Aging 3
3-O-Ethyl Ascorbyl Ether: Advanced Stabilized Vitamin C for Skin Brightening & Anti-Aging 4
3-O-Ethyl Ascorbyl Ether: Advanced Stabilized Vitamin C for Skin Brightening & Anti-Aging 5
3-O-Ethyl Ascorbyl Ether: Advanced Stabilized Vitamin C for Skin Brightening & Anti-Aging 1
3-O-Ethyl Ascorbyl Ether: Advanced Stabilized Vitamin C for Skin Brightening & Anti-Aging 2
3-O-Ethyl Ascorbyl Ether: Advanced Stabilized Vitamin C for Skin Brightening & Anti-Aging 3
3-O-Ethyl Ascorbyl Ether: Advanced Stabilized Vitamin C for Skin Brightening & Anti-Aging 4
3-O-Ethyl Ascorbyl Ether: Advanced Stabilized Vitamin C for Skin Brightening & Anti-Aging 5

3-O-Ethyl Ascorbyl Ether: Advanced Stabilized Vitamin C for Skin Brightening & Anti-Aging

Model No. :  NK-VC

Brand Name:  NIKOOCHEM

Place of Origin:  Guangdong, China

Product Names:  3-O-Ethyl Ascorbyl Ether

INCI: Ethyl Ascorbic Acid

CAS: 86404-04-8

Appearance: White crystalline powder

Solubility (2%): >100g/L in water (20°C) 

Moisture: ≦0.7%

Active ingredient content:  ≧99.3%

pH value (3%):  3.5-6.0

Heavy metal :  <10PPM (Pb)

Toxicity :  Non-toxic and non-irritating

Total bacteria count :  <100CFU/ML

Yeast and mold:  <10CFU/ML

Storage:25°C max, ≤60% RH (sealed)

MOQ :  10kgs/CTN(sample available)

Packaging :  10kgs/CTN 

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    3-O-Ethyl Ascorbyl Ether (Ethyl Ascorbic Acid ): Premium Stabilized Vitamin C Derivative for Clinical-Grade Brightening & Anti-Aging

    Pharma-Grade Purity (≥99.5%) · 15× Higher Bioavailability · Multi-Industry Efficacy

    Product Overview

    Ethyl Ascorbic Acid (CAS 86404-04-8), also known as 3-O-Ethyl Ascorbyl Ether is a high-purity, stabilized vitamin C derivative (≥99% HPLC) engineered to overcome the limitations of traditional L-ascorbic acid. This white crystalline powder combines exceptional water solubility (>100g/L) with unparalleled stability, making it ideal for cosmetics, pharmaceuticals, and functional additives. As a globally trusted ingredient, our product delivers dual-action benefits: inhibiting melanogenesis and boosting collagen synthesis


    VC ethyl ether is a high-purity vitamin C derivative synthesized using a patented one-step synthesis process. Vitamin C is recognized for its highly effective whitening effects and high safety, but it is highly susceptible to oxidation and poorly absorbed by the skin, resulting in low skin utilization. Compared to vitamin C, VC ethyl ether easily penetrates the stratum corneum and enters the dermis. Once in the skin, it is broken down by enzymes to activate the vitamin C's activity, increasing its utilization and achieving enhanced whitening effects

    Core Applications & Benefits

    Key Advantages vs. Conventional Vitamin C

    Unrivaled Stability

    • Resists heat (≤100°C), light, pH fluctuations (3.0-9.0), and oxidation—unlike unstable L-ascorbic acid
    • discoloration or degradation


    Enhanced Skin Penetration

    • Amphiphilic structure penetrates the stratum corneum 3× faster than AA2G, releasing active vitamin C in the dermis
    • Bioavailability: 15× higher than standard vitamin C derivatives


    Triple-Action Efficacy

    1. Brightening: Inhibits tyrosinase’s Cu²⁺ activity, reducing melanin synthesis by 60% at 2% concentration
    2. Anti-Aging: Stimulates collagen synthesis (+45% in fibroblasts), improving elasticity and reducing wrinkles
    3. Antioxidant Protection: Neutralizes free radicals 2× faster than L-ascorbic acid, preventing UV-induced inflammation



    Product Benefits:

    Inhibits tyrosinase activity, inhibits melanin formation, and reduces melanin to a colorless state, effectively whitening the skin.


    VC Ethyl Ether directly participates in collagen synthesis after entering the dermis, repairing skin cell activity and increasing collagen production, thereby plumping and enhancing skin elasticity, leaving it smooth and refined.


    It has excellent antioxidant properties in cosmetics, ensuring optimal utilization of VC. Compared to VC, VC Ethyl Ether is very stable and does not discolor. It truly achieves whitening and freckle removal effects.


    It has potent antibacterial and anti-inflammatory properties, combating sun-induced inflammation.


    Its lipophilic and hydrophilic structure allows for easy skin absorption, penetrating directly into the dermis.


    It is stable and resistant to light, heat, acid, alkali, salt, and air oxidation.


    Applications: Its lipophilic and hydrophilic properties make it highly suitable for formulation. It can be used in gels, serums, lotions, creams, and other skincare products for whitening, freckle removal, anti-aging, and other skincare products.



    Applications & Formulation Guidance

    Cosmetics & Skincare

    • Serums/Creams: 0.5–15% concentration (e.g., The Ordinary 15% serum) for dark spot reduction and radiance .
    • Synergistic Blends:
    1. + 2% Glutathione: Boosts antioxidant defense (e.g., Glowmax Elixir) .
    2. + 0.5% Ectoin: Enhances pollution protection .


    Nutraceuticals & Functional Foods

    • Antioxidant Fortification: 0.3–0.5% in beverages/sports drinks .
    • Natural Preservative: Extends shelf life in meat products (20–30 ppm) .


    Pharmaceuticals

    Wound Healing: 1–5% in ointments to accelerate tissue repair



    Dosage and usage: 0.3-3.0%, add deionized water, stir and dissolve evenly, add at low temperature below 50℃


    Storage & Handling

    Conditions: 25°C max, ≤60% humidity, sealed/light-resistant containers

    Safety: Non-irritating; use gloves/goggles during industrial handling



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