Sodium Hyaluronate – The Gold Standard in Skin Hydration & Barrier Repair
Model No. : Sodium Hyaluronate
Brand Name: NIKOOCHEM
Place of Origin: Guangdong, China
INCI: Sodium Hyaluronate
CAS No.：9067-32-7
Molecular Formula：(C₁₄H₂₀NO₁₁Na)ₙ
Appearance: White to off-white powder or granules
Source：Microbial fermentation (non-animal)
Solubility: Water-soluble (dissolves to form clear, viscous solution)
Purity: ≥90% – 99% (cosmetic grade)
pH (10% solution): 5.0 – 6.0
Recommended dosage: 0.05% – 0.5% (depending on molecular weight)
Shelf Life：Sealed, cool, dry, away from light; 2-year shelf life
MOQ : 1 kg
Packaging : 1 kg/bag
Product Characteristics
A premium, fermentation-derived sodium hyaluronate available across the full molecular weight spectrum – from high molecular weight for surface film-forming to ultra-low molecular weight for deep dermal penetration. The essential ingredient for advanced hydration, anti-aging, and skin barrier formulations.
Sodium Hyaluronate is the sodium salt of hyaluronic acid – the skin’s natural moisture magnet. It is a high-performance humectant that can bind up to 1,000 times its own weight in water, making it one of the most effective moisturising ingredients available to formulators.
Produced through microbial fermentation using non-animal sources, our sodium hyaluronate is pure, sustainable, and biocompatible. It is available across the full molecular weight spectrum, allowing formulators to create multi-dimensional hydration strategies – from surface film-forming to deep dermal penetration.
Why Sodium Hyaluronate?
- Superior Stability: As the sodium salt of hyaluronic acid, it offers enhanced stability and better skin penetration compared to hyaluronic acid
- Full Molecular Weight Portfolio: Choose from high, medium, low, and ultra-low molecular weight grades for targeted performance
- Multi-Depth Hydration: Combine different molecular weights to deliver hydration at every layer of the skin
- Clean & Sustainable: Non-animal derived, fermentation-produced, vegan-friendly, and COSMOS/ECOCERT certified options available
The Science of Hydration
The skin naturally contains hyaluronic acid, predominantly in the dermis, where it acts as a water reservoir – preventing dehydration, tightness, and the formation of fine lines. As we age, natural HA levels decline, leading to dryness, loss of elasticity, and wrinkles.
Sodium hyaluronate replenishes what time takes away.
Each molecule contains numerous hydrophilic groups (hydroxyl groups) that form hydrogen bonds with water molecules, enabling it to retain large quantities of moisture. When applied to the skin, it forms a hydrating film that reduces transepidermal water loss (TEWL) by up to 30%, while allowing oxygen to pass through – avoiding the heavy, occlusive feel of traditional oils and waxes.
Beyond hydration, sodium hyaluronate plays a critical role in the extracellular matrix (ECM), regulating cell-to-cell interactions, promoting epithelial regeneration, modulating inflammatory responses, and scavenging reactive oxygen species (ROS).
Molecular Weight Guide: Choose the Right Grade for Your Formulation
|
Grade |
Molecular Weight |
Function |
Best For |
|
High Molecular Weight (HMW) |
1.0‑1.5 M Da |
Forms a breathable film on the skin surface; locks in moisture; provides instant plumping and a tightening effect |
Day creams, sunscreens, sheet masks, barrier creams |
|
Medium Molecular Weight (MMW) |
50K‑150K Da |
Balances surface hydration with moderate penetration; fills fine lines; provides sustained moisture release |
Serums, lotions, eye creams, daily moisturisers |
|
Low Molecular Weight (LMW) |
<5 kDa |
Penetrates the stratum corneum; delivers deep hydration; transports nutrients to the epidermis
Reaches the dermis; provides intracellular hydration; supports cellular repair and regeneration |
Hydrating serums, ampoules, deep-repair formulas
Intensive anti-aging serums, post-procedure recovery, targeted repair |
Key Benefits
| Benefit | Description |
| 💧 Superior Hydration | Binds up to 1,000 times its weight in water; forms a protective film that reduces moisture loss |
| 🧬 Barrier Repair | Reinforces the stratum corneum, strengthens skin defences, and restores barrier function |
| ✨ Anti-Aging | Plumps fine lines, supports collagen synthesis, and prevents premature aging caused by dehydration |
| 🔄 Cell Regeneration | Promotes wound healing, tissue repair, and epithelial regeneration |
| 🛡️ Anti-Inflammatory | Regulates inflammatory responses and protects cells from oxidative damage |
| 🌿 Biocompatible & Safe | Naturally occurring in the body; non-toxic, non-irritating, suitable for all skin types |
Technical Specifications
| Parameter | Value |
| INCI Name | Sodium Hyaluronate |
| CAS No. | 9067-32-7 |
| Molecular Formula | (C₁₄H₂₀NO₁₁Na)ₙ |
| Appearance | White to off-white powder or granules |
| Solubility | Water-soluble (dissolves to clear, viscous solution) |
| pH (1% solution) | 5.5 – 7.5 |
| Purity | ≥90% – 99% |
| Source | Microbial fermentation (Streptococcus zooepidemicus) |
| Protein content | <0.1% |
| Heavy metals | <10 ppm |
| Microbial limits | <100 cfu/g |
| Recommended dosage | 0.05 – 0.5% (depending on grade) |
| Storage | Sealed, cool, dry, away from light |
| Applications |
Skincare: Serums, essences, moisturisers, eye creams, anti-aging creams, sheet masks, toners, gels Sun Care: Sunscreens, after-sun repair products Hair Care: Shampoos, conditioners, scalp treatments Colour Cosmetics: Foundations, BB/CC creams, concealers, lip products Body Care: Body lotions, hand and foot creams |
| Packaging | 1 kg |
Product Application
Why Choose Our Sodium Hyaluronate?
✅ Full molecular weight portfolio – HMW, MMW, and LMW grades available
✅ Premium purity – high glucuronic acid content, low protein and heavy metal levels
✅ Non-animal origin – produced via microbial fermentation
✅ Sustainable & vegan-friendly – clean, ethical, and environmentally responsible
✅ Technical support – formulation guidance to help you achieve optimal results
Formulation Guidelines
- Dosage: 0.05 – 0.5% (depending on molecular weight and product type)
- Addition: Dissolve in water phase at room temperature or during cool-down
- pH: Stable at pH 4.0 – 8.0
- Temperature: Heat-stable up to 80°C for short periods
- Synergy: Works well with glycerin, panthenol, allantoin, and other humectants
- Multi-MW Strategy: Blend different molecular weights for hydration at all skin layers
Applications:
- Serums, essences, and ampoules
- Moisturisers, creams, and lotions
- Eye creams and anti-aging formulas
- Sheet masks and gel masks
- Sunscreens and after-sun care
- Shampoos, conditioners, and scalp treatments
- Foundations, BB/CC creams, and concealers
Packaging
1kg/bag according to customers' requirements
For samples, it is shipped by express , such as FedEx,DHL,TNT& UPS, it takes around 3-7 days. For bulk order, we will recommend to ship by sea. If you have cooperated shipping agent in China , we can ship to their warehouse for you.
1, the addition amount of 1.0%-10.0% or so, it is recommended that the product is added in the formulation of low temperature (below 55 ℃ when) stage;
2、It is recommended that its package is light-avoidance closed package to reduce contact with air and light sources, sealed storage, and pay attention to reasonable sun protection.
Storage: room temperature (5-25 ℃) to save sealed, shaded cool place to save, 4-5 ℃ refrigeration is preferred. After opening, wipe the bottle clean and store it in airtight refrigerated storage, it is recommended to use it up within 1 month after opening.
Shelf life: the product can remain stable for at least two years when stored in closed containers under the recommended conditions.
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