Dipotassium Glycyrrhizinate: Multifunctional Anti-Inflammatory & Soothing Agent

Natural Origin · Clinically Validated · Cross-Industry Efficacy

Dipotassium glycyrrhizate has anti-inflammatory, antioxidant, antibacterial, wound healing, and effective scavenging of superoxide ions and hydroxyl radicals. It has a wide range of compatibility in cosmetics and is often used with other surfactants to accelerate their absorption by the skin and enhance their effectiveness. It can be used for sun protection, whitening, conditioning, itching relief, moisturizing, etc. There are no side effects with long-term use. It is a high-quality raw material widely used in the pharmaceutical, daily chemical, food and other industries. In addition, this product has the characteristics of high sweetness, good water solubility, low heat energy, good foaming, low hemolysis, and safety and non-toxicity.

Dipotassium Glycyrrhizinate (CAS 68797-35-3) is a high-purity GLYCYRRHIZA URALENSIS (LICORICE)-derived compound (≥98% HPLC) renowned for its potent anti-inflammatory, anti-allergic, and skin-soothing properties. This water-soluble, white-to-off-white powder delivers exceptional stability and versatility across pharmaceuticals, cosmetics, and functional foods, backed by ISO-certified manufacturing and global regulatory compliance

Derived from licorice root (Glycyrrhiza glabra), this high-purity compound (≥98% HPLC, CAS 68797-35-3) delivers triple-action bioactivity:

• Anti-Inflammatory: Inhibits prostaglandin release and HMGB1 signaling
• Anti-Allergic: Suppresses histamine activity and allergy-related genes
• Barrier Repair: Enhances skin hydration and accelerates tissue healing

Key Features

Sustainability: Ethically sourced licorice 

Synergy: Boosts efficacy with Tranexamic Acid or Zinc Oxide

Versatility: Water-soluble powder for diverse formulations

Ideal for brands targeting "clean beauty," clinical skincare, and functional nutrition.

Main Applications:

1. Pharmaceutical Industry: Used for cough and expectoration, gastric ulcers, acute and chronic gastritis, eczema, itchy skin, hepatitis, hyperlipidemia, conjunctivitis, and in eye drops and stomatitis ointments.

2. Cosmetics Industry: Used to prevent dermatitis, dry skin, sunburn, rashes, and soothe the throat. It is also used as a freckle remover and anti-allergic agent. It blocks the release of histamine and has detoxifying, disinfecting, and anti-allergic effects, similar to the effects of adrenal cortex hormones, but with no side effects even with long-term use. It has multiple functions, including antibacterial, anti-inflammatory, detoxifying, anti-allergic, and deodorizing. It is used in anti-allergic, sunscreen, and freckle removal creams, lotions, skin toners, and face creams. 3. Licorice extract activates corticosteroids (inhibiting metabolic enzymes), indirectly enhancing their effects. It can be used in all cosmetics, including creams, lotions, lotions, milks, and honeys. It can neutralize, eliminate, or reduce toxic substances in cosmetics and prevent allergic reactions to some cosmetics. It is particularly suitable for use in high-end hair and skin cosmetics.

Safety Advantage: Non-irritating at ≤0.5% – ideal for sensitive skin formulations.

• Conditions: 25°C max, ≤60% humidity, sealed/light-resistant containers
• Safety: Non-irritating; use gloves/goggles during industrial handling

Instructions: Dissolve this product in a small amount of water at room temperature and add to the cosmetic formula according to the process requirements.

Dosage: 0.1-3%