POLYSORBATE 80: Premium Non-Ionic Surfactant for Pharmaceutical, Cosmetic & Industrial Applications
Model No. : NK-3984
Brand Name: NIKOOCHEM
Place of Origin: Guangdong, China
Product Names: POLYSORBATE 80
INCI: POLYSORBATE 80
CAS No.: 9005-65-6
Molecular formula: C24H44O6
Molecular weight: 1309.68
Appearance: Amber to orange viscous liquid
Heavy Metals: ≤10 ppm
Acid Value: ≤2.2 mg KOH/g
Moisture: ≤3.0%
HLB Value： 15.0
Purity：≥99%
Solubility：Water, ethanol, methanol; insoluble in mineral oil
Viscosity (25°C): 350–550 mm²/s
Storage：2 years (sealed, <25°C)
MOQ : 25kgs(sample available)
Packaging : 25kg drum
POLYSORBATE 80: Premium Non-Ionic Surfactant for Pharmaceutical, Cosmetic & Industrial Applications
HLB 15.0 · Multi-Functional Solubilizer & Emulsifier · Global Compliance
Product Overview
NIKOO's Polysorbate 80 (INCI: Polysorbate 80, CAS 9005-65-6), also known as Tween 80, is a high-purity, non-ionic surfactant derived from polyethoxylated sorbitan and oleic acid. This versatile amber viscous liquid (HLB 15.0) excels as an emulsifier, solubilizer, and stabilizer across pharmaceuticals, cosmetics, and food industries. Engineered for optimal performance, it meets stringent pharmacopeial standards (CP2000, USP) with batch-to-batch consistency
Basic Properties
Chemical Structure: Partially esterified and polymerized sorbitol, ethylene oxide, and oleic acid. Average molecular weight: 1309.68.
Appearance: Pale yellow to orange-yellow viscous liquid, readily soluble in water, ethanol, and other organic solvents, insoluble in mineral oil.
Physical Parameters:
- Relative density: 1.06-1.09;
- Kinematic viscosity: 350-550 mm²/s at 25°C;
- Saponification value: 45-55, hydroxyl value: 65-80.
Core Applications & Benefits
Core Applications
Pharmaceuticals
Injectables & Oral Liquids: Solubilizer for poorly soluble APIs (≤2% concentration) .
Topical Formulations: Emulsifier in ointments, creams, and otic suspensions (e.g., steroid-antibiotic combinations) .
Safety Note: Strictly limit to 100 μg/mL in injectables to avoid hypersensitivity risks .
Cosmetics & Personal Care
Emulsion Stabilizer: Water-in-oil (W/O) systems for serums and moisturizers.
Sensory Enhancer: Improves spreadability in luxury creams .
Functional Applications
Pharmaceutical Excipient: Widely used in liquid, semi-solid, and solid dosage forms as an O/W emulsifier, solubilizer, wetting agent, and stabilizer, meeting FDA standards.
Industrial Uses: Used as an emulsifier and dispersant, improving the dispersion of phthalocyanine green.
Safety
Toxicity: Low toxicity, may cause allergic reactions or injection site discomfort.
Storage: Store in a sealed, dry place, away from high temperatures.
Specifications
Purity: Pharmaceutical grade can reach 99.9%, while industrial grade typically reaches 99% purity.
Storage & Handling
Conditions: 25°C max, ≤60% humidity, sealed/light-resistant containers
Safety: Non-irritating; use gloves/goggles during industrial handling
Contact Us:
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