SORBITAN OLEATE (Span 80): Premium Non-Ionic Emulsifier for Pharmaceuticals, Cosmetics & Industrial Applications
Model No. : NK-5925
Brand Name: NIKOOCHEM
Place of Origin: Guangdong, China
Product Names: Span 80
Other Names: armotanmo;emsorb2500;EmulsifierS80;glycomulo;ionets80;sorbons80;sorgen40;Arlacel 80 Sorbitan Monooleate
INCI: SORBITAN OLEATE
CAS No.: 1338-43-8; 37318-79-9
Molecular formula: C24H44O6
Molecular weight: 428.6
Appearance: Amber viscous liquid
Acid Value: ≤2.2 mg KOH/g
Moisture: ≤1.0%
HLB Value： 4.3
Purity：≥98%
Heavy metal : <10PPM (Pb)
Storage：2 years (sealed, <25°C)
MOQ : 25kgs(sample available)
Packaging : 25kg drum
SORBITAN OLEATE (Span 80): Premium Non-Ionic Emulsifier for Pharmaceuticals, Cosmetics & Industrial Applications
HLB 4.3 · W/O Emulsion Specialist · Global Compliance
Product Overview
Sorbitan oleate is a surfactant formed by the esterification of dehydrated sorbitol with oleic acid. Also known as Span 80, its CAS number is 1338-43-8.
Chemical Properties
Molecular Structure: An ester compound formed by dehydrated sorbitol with oleic acid. The molecular formula is C₂₄H₄₄O₆, and its molecular weight is 464.63.
Appearance: Pale yellow to yellow oily liquid with a slight odor. Insoluble in water and propylene glycol.
Physical and Chemical Properties
Acid Value: ≤8 (General Rule 0713).
Hydroxy Value: 190-215 (General Rule 0713).
Saponification Value: 145-160 (saponification time: 1 hour).
Iodine Value: 62-76 (General Rule 0713). Peroxide Value: ≤10 (General Rule 0713)
SORBITAN OLEATE is a yellow oily liquid that is readily soluble in water, ethanol, methanol, or ethyl acetate, and very slightly soluble in mineral oil. It is a w/o emulsifier with strong emulsifying, dispersing, and lubricating properties. It can be mixed with various surfactants, and is particularly effective when used in combination with Tween-60. HLB value: 4.7, melting point: 52-57°C.
Core Applications & Benefits
Pharmaceuticals
Injectable Solutions: Solubilizer for hydrophobic APIs (≤2% concentration); strictly limit to 100 μg/mL to avoid hypersensitivity risks .
Topical Ointments: Stabilizes W/O emulsions in corticosteroid-antibiotic combinations (e.g., Neomycin/Polymyxin B/Hydrocortisone) .
Cosmetics & Personal Care
W/O Emulsions: Creates stable creams and sunscreens (CIR-safe: ≤7.7% leave-on, ≤0.88% rinse-off) .
Safety Note: Comedogenic risk at high doses; optimize at ≤4% to prevent pore clogging
An excellent oil-in-water emulsifier. Used as a gas chromatography stationary phase (maximum operating temperature 150°C, methanol as solvent) for separating and analyzing oxygenated compounds. Also used as a stabilizer. Also used as a thickener in foods, cosmetics, and pharmaceuticals. Also used as a fiber lubricant and softener in the textile industry.
Storage & Handling
Conditions: 25°C max, ≤60% humidity, sealed/light-resistant containers
Safety: Non-irritating; use gloves/goggles during industrial handling
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