Ascorbyl Tetraisopalmitate (VC-IP) - Premium Oil-Soluble Vitamin C Derivative

Next-Generation Antioxidant & Brightening Active for Advanced Skincare Formulations

Our Ascorbyl Tetraisopalmitate (INCI: Ascorbyl Tetraisopalmitate, CAS: 183476-82-6), also known as Tetrahexyldecyl Ascorbate or VC-IP, is a high-purity, oil-soluble vitamin C derivative that represents the most advanced innovation in antioxidant and brightening skincare technology. As a pioneering Chinese manufacturer, we have developed a proprietary synthesis process that delivers VC-IP with exceptional purity (≥95-99%) and unmatched stability compared to traditional vitamin C derivatives .

This revolutionary ingredient offers direct biological activity with superior skin penetration and conversion to free vitamin C within the skin, making it significantly more effective and less irritating than conventional vitamin C forms such as L-ascorbic acid or water-soluble derivatives . Our VC-IP is specially engineered for formulators seeking to create high-performance skincare products that deliver visible brightening and anti-aging results without causing stability issues or formulation challenges associated with traditional vitamin C .

With its unique molecular structure that features four isopalmitic acid chains, our VC-IP provides exceptional oil solubility, enhanced skin permeability, and prolonged antioxidant activity in cosmetic formulations, making it the ideal choice for brands targeting consumers who seek clinical-grade results without compromise on stability or skin compatibility

Our Ascorbyl Tetraisopalmitate is manufactured through a proprietary enzymatic synthesis technology that combines green chemistry principles with advanced purification techniques:

1. Enzyme Selection & Optimization: We utilize specially selected immobilized lipases (such as Novozyme 435) that demonstrate high catalytic activity for the esterification reaction between ascorbic acid and isopalmitic acid in non-aqueous media .
   
2. Controlled Esterification: The esterification process is conducted under precisely controlled conditions (temperature, pressure, and reaction time) to ensure optimal conversion rates while preserving the integrity of the vitamin C molecule .
   
3. Advanced Purification: The crude product undergoes multi-stage purification using specialized molecular distillation and chromatographic techniques. This process ensures the removal of impurities while maintaining the structural integrity of the VC-IP molecules .
   
4. Quality Enhancement: The purified VC-IP undergoes a stabilization process that enhances shelf stability and ensures consistent performance in final formulations. This includes careful control of oxygen exposure and light protection during processing .
   
5. Comprehensive Quality Control: Each batch undergoes rigorous analytical testing including HPLC for purity assessment, GC-MS for contaminant screening, and stability testing under various conditions to ensure compliance with stringent quality standards
   

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As a leading manufacturer of advanced skincare active ingredients, we offer distinct advantages that make us the preferred partner for skincare brands worldwide:

• Proprietary Enzymatic Technology: Our advanced enzymatic synthesis platform enables production of VC-IP with exceptional purity and minimal environmental impact, avoiding the harsh conditions and impurities associated with chemical synthesis methods .
  
• Extensive Research Capabilities: With dedicated R&D centers and experienced chemical engineers, we maintain continuous innovation and product improvement, holding multiple patents related to enzymatic synthesis and purification technologies .
  
• Significant Production Capacity: With large-scale production facilities (3300+ tons/year capacity) and fully automated production lines, we can reliably supply both small development quantities and large commercial volumes with consistent quality
• Customization Flexibility: We offer VC-IP in various purity grades (95%, 98%, 99%) and can provide custom formulations tailored to specific application needs .
  
• Global Logistics Expertise: Established export expertise with efficient shipping solutions to major international markets, supported by comprehensive documentation including certificates of analysis, safety data sheets, and customs documentation 

Our Ascorbyl Tetraisopalmitate offers exceptional performance characteristics that make it ideal for advanced skincare formulations:

Superior Stability

Unlike traditional vitamin C which is prone to rapid oxidation and degradation, our VC-IP demonstrates exceptional stability against heat, light, and oxygen exposure. It maintains efficacy throughout product shelf life without discoloration or loss of potency

Enhanced Skin Penetration

The lipophilic nature of VC-IP allows for excellent skin permeability and absorption. Once absorbed, it undergoes enzymatic conversion to release free vitamin C within the skin, ensuring targeted delivery to where it's most needed

Multi-Action Benefits

Beyond antioxidant protection, VC-IP provides comprehensive skincare benefits:

• Inhibits tyrosinase activity and melanin production for significant brightening effects 
  
• Stimulates collagen synthesis for improved skin firmness and reduction of fine lines 
  
• Protects against UV-induced damage and reduces DNA damage from sun exposure 
  
• Prevents lipid peroxidation and cellular damage from environmental stressors 
  
• Exhibits SOD-like activity for enhanced antioxidant defense mechanisms 

Formulation Versatility

Our VC-IP is compatible with various formulation systems including:

• Anhydrous formulations (oils, serums, balms)
  
• Oil-in-water and water-in-oil emulsions
  
• Various cosmetic oils with excellent solubility characteristics 
  
• Advanced delivery systems for enhanced targeted effects

Excellent Safety Profile

Rigorous safety testing confirms that our VC-IP is well-tolerated and suitable for all skin types, including sensitive skin. Its natural metabolic pathway ensures biocompatibility without irritation

Our Ascorbyl Tetraisopalmitate is suitable for a wide range of skincare applications:

Recommended Product Categories

• Brightening serums and dark spot correctors
  
• Anti-aging treatments and rejuvenating creams
  
• Antioxidant boosters and daily protection products
  
• Luxury facial oils and intensive treatments
  
• Eye care products for dark circle reduction
  
• Sun care products for enhanced UV protection
  
• After-sun treatments for repair and recovery

Formulation Recommendations

Table: Formulation Guidelines for Different Applications

Synergistic Combinations

For enhanced benefits, combine VC-IP with:

• Vitamin E (Tocopherol) for synergistic antioxidant protection 
  
• Niacinamide for improved barrier function and enhanced brightening
  
• Hyaluronic acid and ceramides for multi-level hydration and barrier support
  
• Other antioxidants like ferulic acid for comprehensive protection
  
• Peptides for synergistic anti-aging effects

Stability Considerations

To maximize stability and performance in formulations:

• Maintain pH below 6.0 in formulations 
• Use chelating agents (e.g., EDTA) to prevent metal-catalyzed oxidation 
• Incorporate appropriate antioxidants in the formulation system
• Avoid prolonged heating above 60°C during manufacturing 
• Use appropriate packaging (airless containers, UV protection) to preserve efficacy

We offer flexible ordering options to meet diverse customer needs:

• Sample Availability: Available in 25g, 50g, and 100g sizes for formulation development

• Minimum Order Quantity (MOQ): 1kg for standard material

• Standard Packaging: 1kg aluminum bottles with nitrogen headspace for optimal preservation 

• Customization Options:

1. Different purity grades (95%, 98%, 99%)
2. Customized documentation packages
3. Exclusive rights for large volume orders
4. Private labeling and OEM services

• Lead Times: Samples within 3-5 business days, production quantities in 2-3 weeks

Our technical support team provides comprehensive assistance including:

• Formulation guidance and compatibility testing
• Regulatory support for different markets (EU, USA, ASEAN, etc.)
• Stability testing protocols and assistance
• Claims support with clinical data references
• Custom development for specific application needs

Ready to enhance your formulations with premium Ascorbyl Tetraisopalmitate?

Contact our technical specialists today to discuss your specific requirements, request samples, or obtain detailed technical documentation.

Please include in your inquiry:

• Your company information and intended applications
• Required quantity and specifications
• Any specific customization needs
• Target markets and regulatory requirements

We respond to all inquiries within 24 business hours and are committed to building long-term partnerships through superior products and technical support.