ASM Cytokine solves the symptoms of skin aging, sensitivity and dryness.

Product Characteristics

R&D Background

With age, keratin-containing substances such as skin and hair age, feeding back through changes in their structure and function.

Endogenously, keratin substances are attacked by superoxide ions, which are naturally produced during physiological cellular metabolism.

Exogenously, keratin substances are exposed to environmental factors involved in their aging including UV radiation, or atmospheric pollution.

Extrinsic aging of environmentally affected skin superimposes age-related intrinsic aging, causing characteristic skin damage and changes.

Skin Care Principles

• Breaking through the skin's 28-day physiological metabolic cycle, completing the renewal of the stratum corneum in 14 days and minimizing fine lines.
  
• Participate in the construction of healthy skin micro-ecology, fully enhance the skin's ability to resist external stimuli.
  
• Outstanding repair and antioxidant capacity
  
• Increase the skin's utilization of oxygen, promote cell growth and product synthesis, thus making the skin more youthful

Micrococcus sp. active secretion

By inducing an increase in the endogenous synthesis of superoxide dismutase, with a lipopolysaccharide-containing cytosol of bacteria of the genus Micrococcus with an extracellular active secretion, in order to obtain in particular the prevention or treatment of signs of aging of the skin, such new active secretion is able to reactivate the regeneration of the epidermis by inducing the proliferation of keratin-forming cells. The ability to maintain or even enhance the barrier properties of the skin by repairing skin damage From the point of view of reducing and/or delaying skin aging, the clarified secretion obtained from the biomass of the bacteria of the genus Micrococcus shows excellent results in skin physiology against skin aging.

The present material relates to the technical field of fermentation of bacteria of the genus Micrococcus, specifically to a method of obtaining a fermentation broth and a lysate of bacteria of the genus Micrococcus and to its application in anti-ageing

Micrococcus spp. bacteria are biocultured in complete medium to obtain a large amount of biomass of Micrococcus spp. bacteria, and then the biomass of Micrococcus spp. bacteria is hydrolyzed by pyrolysis and protein hydrolysis to obtain a lysate the lysate is clarified to obtain a clarified lysate, and then the clarified lysate is purified to obtain a Micrococcus spp. bacterial fermentation lysate.

Micrococcus active secretion was originally developed to be able to reactivate epidermal regeneration by inducing proliferation of keratin-forming cells, thereby promoting stratum corneum metabolism and rapidly crowding out old stratum corneum cells with newborn cells. Further surprises revealed that the micrococcal fermentation lysate was able to positively contribute to the skin's microecological balance, inferring that the LPS of one or more lipids in the micrococcal bacterium was able to stimulate the expression of anti-microbial peptides in keratinized cells of the skin, thereby increasing the skin's resistance to the outside world and stress.

Micrococcus outer membrane lipopolysaccharide (LPS) mimics some of the activities of intact bacteria to stimulate immune cells to replenish and activate a certain population of lymphocytes.

Briefly, the LPS of Micrococcus outer membrane lipids stimulates the expression of anti-microbial peptides in keratinized skin cells and is able to activate the skin defense system without producing defects related to the intrinsic activity of pathogens or intact bacteria.

It has been shown that the active secretion of Micrococcus spp. counteracts skin dryness and sensitization and restores the skin barrier and the diversity of microorganisms on the skin surface. Based on the above micro-ecological antimicrobial mechanism, Micrococcus Active Secretion can be used to:Limit the proliferation of pathogenic skin microorganisms in seborrheic states, especially those maintaining oily skin or oily scalp phenomena. For the prevention or limitation of dandruff symptoms / for the improvement of oral hygiene / for the regulation of the microbial balance in the intimate area / for the limitation of unpleasant odors associated with the proliferation of skin microorganisms in the closed position.

The addition of 2.0% of Micrococcus sp. active secretion, used in the morning and evening trial of 28 sensitive skin, all feedback after use, significantly relieve the symptoms of dry and sensitive skin, in a week after the sensitive symptoms effectively reduced.