Centella Asiatica Ferment Filtrate – Fermented Centella for Superior Wound Healing, Anti‑Inflammation & Skin Repair
A lactobacillus‑fermented Centella asiatica leaf extract – higher active yields than conventional extraction. Proven to scavenge free radicals, inhibit hyaluronidase (95.45%), and accelerate wound healing by promoting collagen synthesis and reducing inflammation.
Product Overview:
Centella asiatica (also known as Gotu Kola) has been used for centuries to treat skin wounds, burns, and inflammation. Its key actives – asiaticoside, madecassoside, asiatic acid, and madecassic acid – are well known for promoting collagen synthesis, reducing scar formation, and calming irritation. However, traditional extraction methods (alcohol or ultrasound) can degrade delicate actives or leave residual solvents.
Our Centella Asiatica Ferment Filtrate is produced using microbial fermentation (lactobacillus). This gentle, biomimetic process:
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Preserves the natural structure of active compounds.
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Increases extraction yield of total triterpenes and madecassoside (as shown in comparative data).
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Adds beneficial bacterial metabolites (organic acids, peptides, polysaccharides) that enhance skin compatibility and efficacy.
| Benefit | Mechanism / Data |
|---|---|
| 🌿 Powerful antioxidant | DPPH radical scavenging: 51.6% at 2.5% → 85.81% at 15% concentration |
| ⚡ Hydroxyl radical scavenging | ·OH scavenging: 50.36% at 2.5% → 67.83% at 15% |
| 🛡️ Anti‑allergy / anti‑sensitive | Inhibits hyaluronidase (enzyme that degrades hyaluronic acid and triggers inflammation) by 95.45% at 30% concentration |
| 🩹 Accelerates wound healing | Increases hydroxyproline content in wound tissue; suppresses pro‑inflammatory cytokines; promotes organised collagen fibre deposition |
| 🧬 Promotes cell migration & proliferation | Enhances keratinocyte and fibroblast migration; shortens wound closure time |
| 💧 Soothing & barrier repair | Calms redness, irritation, and sensitivity; ideal for compromised skin |
| Method | Total Triterpene Yield | Active Integrity | Solvent Residue |
|---|---|---|---|
| Alcohol extraction | Moderate | May degrade | Present |
| Ultrasound extraction | Higher | Risk of thermal degradation | None but expensive |
| Fermentation (our process) | Highest | Preserved | None, clean label |
Proven Efficacy Data:
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DPPH radical scavenging: 85.81% at 15% ferment concentration.
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Hydroxyl radical scavenging: 67.83% at 15% ferment concentration.
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Hyaluronidase inhibition: 95.45% at 30% ferment concentration – prevents degranulation of mast cells and reduces allergic/inflammatory responses.
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Wound healing (animal model): Increased hydroxyproline (collagen marker) in wound tissue; reduced pro‑inflammatory cytokines; collagen fibres became dense, evenly arranged, and organised; accelerated healing time.
| Parameter | Value |
|---|---|
| INCI Name | Centella Asiatica Leaf Extract, 1,2‑Hexanediol, Butylene Glycol, Hydroxyacetophenone |
| Composition | 97.3% ferment filtrate + preservatives |
| Appearance | Clear to pale yellow liquid |
| Odour | Characteristic (earthy, herbal) |
| Solubility | Water‑soluble |
| pH (recommended) | ~6.0 |
| Recommended dosage | 30 – 85% (can be used as a high‑concentration base) |
| Addition temperature | <50°C (to preserve bioactivity) |
| Stability | Protect from light and high heat (may slightly discolour) |
| Safety | Non‑irritating (eye/skin); suitable for sensitive skin |
| Applications | Toners, essences, serums, masks, creams, after‑sun care, post‑laser repair, wound healing sprays |
Why Formulators Choose This Fermented Centella:
✅ Higher active yield – more effective than simple extracts.
✅ Clean label – no organic solvents, mild preservation.
✅ Multi‑functional – antioxidant, anti‑inflammatory, anti‑allergy, wound healing, barrier repair.
✅ Clinically‑inspired – hyaluronidase inhibition at 95.45% is exceptional.
✅ Easy to formulate – water‑soluble, can be used at high levels (up to 85%).
Formulation Guidelines:
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Dosage: 30 – 85% (30‑50% for daily soothing; 50‑85% for intensive repair).
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Addition: Add to water phase at <50°C.
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pH: Adjust to ~6.0 for optimal stability.
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Applications:
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Soothing & anti‑redness toners / mists
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Wound healing gels or sprays
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Post‑laser / post‑procedure recovery masks
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Anti‑aging & repair serums
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Sensitive skin creams
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Packaging & Storage:
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Packaging: 30 kg / drum
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Storage: Room temperature, sealed, dark; avoid prolonged light/heat
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Shelf life: 24 months
Centella Ferment – The power of centella, amplified by fermentation, for skin that heals faster and stays calmer.
