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NIKOO Chemical - Skincare Raw Material Supply and Custom Solution Specialist for 15 years. 

Cordyceps Mycelium Ferment Filtrate – Potent Anti‑Inflammatory & Anti‑Aging Ferment for Sensitive & Mature Skin

A high‑density fermentation of Cordyceps sinensis mycelium – rich in bioactive heteropolysaccharides. Proven to scavenge 98.6% of superoxide anions, reduce nitric oxide (NO) release, inhibit acute inflammation by 50%, and improve skin density, hydration, and elasticity.

Cordyceps Mycelium Ferment Filtrate – Potent Anti‑Inflammatory & Anti‑Aging Ferment for Sensitive & Mature Skin 1

Product Overview:
Cordyceps sinensis has been treasured in traditional medicine for centuries. Our Cordyceps Mycelium Ferment Filtrate is produced using proprietary deep‑liquid high‑density fermentation technology, yielding a potent bioactive liquid rich in heteropolysaccharides (rhamnose, xylose, mannose, glucose, galactose), glycoproteins, and proteoglycans. Unlike simple extracts, this ferment filtrate offers superior bioavailability and multi‑targeted skin benefits:

  • Antioxidant power – scavenges superoxide anions (O₂⁻) with up to 98.6% efficiency at 100 mg/mL.

  • Anti‑inflammatory – significantly reduces LPS‑induced NO release in RAW264.7 macrophages (concentration‑dependent, p<0.01).

  • Reduces acute inflammation – inhibits TPA‑induced mouse ear swelling by 50% (at 50% concentration).

  • Anti‑aging & skin regeneration – in a 6‑month human study (n=28):

    • Crow’s feet reduced by 16‑19%

    • Skin density increased by 20‑24%

    • Skin plumpness improved by 18‑21%

  • Barrier repair & hydration – after 28 days of use (30% ferment in a lotion):

    • Stratum corneum water content ↑ 31%

    • TEWL ↓ 14 g/m²h

    • Elasticity coefficient (R) ↑ 35%

Key Benefits at a Glance:
Benefit Mechanism / Data
⚡ Superoxide scavenging 98.6% elimination (100 mg/mL) – protects against oxidative stress
🔥 Anti‑inflammatory Reduces NO release in macrophages (p<0.01); inhibits TPA‑induced ear swelling by 50%
🧬 Anti‑aging 6‑month clinical: crow’s feet ↓16‑19%, skin density ↑20‑24%, plumpness ↑18‑21%
💧 Hydration & barrier 28‑day test: moisture ↑31%, TEWL ↓14 g/m²h, elasticity ↑35%
🌿 Soothing sensitive skin Calms irritation, modulates immune response, reduces redness
🧴 High versatility Can be used at 20‑100% as a base for toners, essences, masks, and creams
Technical Specifications:
Parameter Value
Product name Cordyceps Mycelium Ferment Filtrate
INCI Name Cordyceps Sinensis Extract, 1,2‑Hexanediol, Butylene Glycol, Hydroxyacetophenone
Composition 97.4% ferment filtrate + preservatives
Appearance Clear to pale yellow liquid
Odour Characteristic (earthy, mushroom‑like)
Solubility Water‑soluble
pH (recommended) ~5.5
Recommended dosage 20 – 100% (can be used as a complete base)
Addition temperature <60°C (to preserve bioactivity)
Stability Protect from light and high heat (may slightly discolour over time)
Safety Non‑irritating (eye/skin); safe for sensitive skin
Applications Toners, essences, serums, masks, creams, after‑sun care, post‑procedure repair

Why Formulators Choose Cordyceps Ferment:
✅ High potency – 98.6% superoxide scavenging, clinically proven anti‑aging.
✅ Multi‑functional – anti‑inflammatory, antioxidant, barrier repair, anti‑wrinkle.
✅ Safe & gentle – no irritation, suitable for sensitive and reactive skin.
✅ Easy to formulate – water‑soluble, can be used at high concentrations (up to 100%).

Formulation Guidelines:

  • Dosage: 20 – 100% (30‑100% recommended for optimal efficacy).

  • Addition: Add to water phase at <60°C.

  • pH: Adjust to ~5.5 for best stability.

  • Applications:

    • Anti‑aging & firming serums

    • Soothing toners for sensitive skin

    • Post‑laser / post‑procedure recovery masks

    • Hydrating & barrier repair lotions

    • High‑performance sheet mask bases

Packaging & Storage:

  • Packaging: 30 kg / drum

  • Storage: Room temperature, sealed, dark; avoid prolonged light/heat

  • Shelf life: 24 months

Cordyceps Ferment – The power of cordyceps, unlocked by fermentation, for skin that ages gracefully and heals quickly.

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