Fermented Tremella fuciformis polysaccharide Trepoly-01 cosmetics raw material

Tremella fuciformis polysaccharide is the main active ingredient in Ginkgo biloba, the main chain is mannan connected by α-(1→3)-glycosidic bond, and the side chain consists of xylose, glucose, fucose, and glucuronic acid, etc., which has a variety of biological activities, and the degree of polymerization ranges from more than 200,000 to more than 1400,000,000 degrees.

The aqueous solution presents a colorless, transparent, tasteless and odorless viscous liquid, with good stability at both high and low temperatures, and a wide pH adaptation range.

NIKOO's Trepoly-01 Tremella fuciformis polysaccharide is a relatively low molecular weight Tremella fuciformis polysaccharide with an average molecular weight of about 340,000 Daltons and a weight average molecular weight of 566,8066 Da after instrumental testing. Analyzing the molecular weight range based on the slice data, it can be seen that NIKOO's Trepoly-01 contains both low molecular weight and high molecular weight Tremella fuciformis polysaccharide

Tremella fuciformis polysaccharide plays an antioxidant role by scavenging free radicals and increasing the activity of antioxidant enzymes. By protecting the antioxidant enzymes and thus reducing water loss, improving skin structural changes, and increasing the content of type I collagen, it proves its ability to enhance the antioxidant capacity of the organism.

Tremella fuciformis polysaccharide has unique advantages in preventing and improving inflammation, such as multi-pathway, multi-targeting, low toxicity and few side effects. It can inhibit the pro-inflammatory signaling pathway and reduce the production of pro-inflammatory factors, thus playing an anti-inflammatory role.

It was found that Tremella fuciformis polysaccharide inhibits TLR4/Akt/MAPK/NF-κB pro-inflammatory signaling pathway and regulate RAW264.7 and Foxp3+ T cells thus reducing the production of inflammatory factors TNF-α, IL-6 and COX-2.

Tremella fuciformis polysaccharide is hygroscopic and moisturizing, their hygroscopic properties cause them to draw water from the environment, thus increasing the skin's moisture content. It also has film-forming properties, which locks in moisture and prevents it from evaporating, resulting in a moisturizing effect.