Hydroxypinacolone Retinoate (HPR) - Premium Anti-Aging Active Ingredient

Next-Generation Retinoid for Advanced Skincare Formulations

Our Hydroxypinacolone Retinoate (HPR) [CAS: 893412-73-2] is a revolutionary retinoid derivative that represents the latest advancement in anti-aging skincare technology. As a pioneering Chinese manufacturer, we have developed a proprietary synthesis process that delivers HPR with exceptional purity (≥99%) and unmatched bioactivity without the traditional drawbacks associated with retinoid compounds .

This next-generation ingredient offers direct biological activity by binding to retinoic acid receptors (RARs) without requiring enzymatic conversion, making it significantly more effective and less irritating than conventional retinoids like retinol or retinoic acid. Our HPR is specially engineered for formulators seeking to create high-performance skincare products that deliver visible anti-aging results within 14 days without causing sensitivity or irritation, even in delicate eye area formulations .

With its unique molecular structure that combines hydroxypinacolone with retinoic acid, our HPR provides superior stability, enhanced skin penetration, and prolonged activity in cosmetic formulations, making it the ideal choice for brands targeting consumers with sensitive skin who cannot tolerate traditional vitamin A products 

Our HPR is manufactured through a proprietary synthetic biology approach that combines precision chemistry with advanced purification technologies:

1. Molecular Synthesis: We utilize a patented synthesis process that begins with high-purity retinoic acid and hydroxypinacolone, employing green chemistry principles to minimize environmental impact and maximize yield
   
2. Precision Esterification: Through controlled reaction conditions including specific temperature and pressure parameters, we achieve optimal esterification between the retinoic acid and hydroxypinacolone components, ensuring consistent molecular structure and biological activity in every batch
   
3. Advanced Purification: The crude product undergoes multi-stage purification using specialized chromatographic techniques and solvent systems. This process ensures the removal of impurities while maintaining the structural integrity of the HPR molecules 
   
4. Quality Enhancement: The purified HPR undergoes a proprietary stabilization process that enhances shelf stability and ensures consistent performance in final formulations. This includes precise control of crystal structure for powder forms and emulsification for liquid formulations
   
5. Comprehensive Quality Control: Each batch undergoes rigorous analytical testing including HPLC for purity assessment, GC-MS for contaminant screening, and stability testing under various conditions to ensure compliance with stringent quality standards

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As a leading manufacturer of bioactive skincare ingredients, we offer distinct advantages that make us the preferred partner for skincare brands worldwide:

• Proprietary Synthesis Technology: Our advanced chemical synthesis platform enables production of HPR with exceptional purity (≥99%) and batch-to-batch consistency, ensuring reliable performance in cosmetic formulations
  
• Extensive Research Capabilities: With dedicated R&D centers and experienced chemical engineers, we maintain continuous innovation and product improvement, holding multiple patents related to HPR production and application
  
• Significant Production Capacity: With large-scale production facilities and fully automated production lines, we can reliably supply both small development quantities and large commercial volumes with consistent quality
  
• Customization Flexibility: We offer HPR in various formulations including powder form (≥99% purity) and liquid solutions (10% concentration in oil bases) to meet different formulation needs
• Global Logistics Expertise: Established export expertise with efficient shipping solutions to major international markets, supported by comprehensive documentation including certificates of analysis, safety data sheets, and customs documentation 

Our Hydroxypinacolone Retinoate offers exceptional performance characteristics that make it ideal for advanced skincare formulations:

Superior Efficacy Without Irritation

HPR directly binds to retinoic acid receptors (RARs) without requiring enzymatic conversion, providing immediate biological activity without the irritation typically associated with traditional retinoids. This makes it suitable even for sensitive skin and eye area applications

Rapid Anti-Aging Results

Clinical data demonstrates visible anti-wrinkle results within 14 days of regular use. HPR promotes collagen synthesis, accelerates cell renewal, and reduces wrinkles and fine lines more effectively than conventional retinoids while being significantly less irritating

Enhanced Stability

Unlike traditional retinoids which are prone to degradation when exposed to light and air, our HPR demonstrates exceptional stability in various formulation bases, maintaining efficacy throughout product shelf life

Multi-Action Benefits

Beyond anti-aging, HPR provides comprehensive skincare benefits:

• Regulates sebum production for improved acne management 
• Lightens hyperpigmentation and evens skin tone 
• Strengthens skin barrier function for better hydration 
• Provides antioxidant protection against environmental stressors 

Formulation Versatility

Our HPR is compatible with various formulation systems including:

• Anhydrous formulations (using powder form)
  
• Oil-based serums (using liquid solution form)
  
• Water-in-oil and oil-in-water emulsions
  
• Advanced delivery systems for enhanced penetration

Excellent Stability

Rigorous safety testing confirms that our HPR is non-irritating and suitable for sensitive skin types, including those who cannot tolerate other vitamin A derivatives 

Our Hydroxypinacolone Retinoate is suitable for a wide range of skincare applications:

Recommended Product Categories

• Anti-aging creams and serums for face and eye area
  
• Acne treatments and blemish control products
  
• Brightening formulations for hyperpigmentation
  
• Night repair treatments and intensive creams
  
• Prevention products for premature aging
  
• Neck and décolletage treatments

Formulation Recommendations

Table: Formulation Guidelines for Different Applications

Synergistic Combinations

For enhanced benefits, combine HPR with:

• Niacinamide for improved barrier function and redness reduction
  
• Hyaluronic acid and ceramides for multi-level hydration
  
• Antioxidants like vitamin C and E for comprehensive protection
  
• Peptides for synergistic anti-aging effects
  
• Sun filters in day products for photoprotection

We offer flexible ordering options to meet diverse customer needs:

• Sample Availability: Available in 25g, 50g, and 100g sizes for formulation development
• Minimum Order Quantity (MOQ): 1kg for standard material, 5kg for customized versions
• Standard Packaging: 1kg aluminum bags with PE liner, 5kg and 25kg containers
• Customization Options:

1. Purity levels (95%, 98%, 99%)
2. Various concentration solutions (5%, 10%, 20%)
3. Customized documentation packages
4. Exclusive rights for large volume orders

• Lead Times: Samples within 3-5 business days, production quantities in 2-3 weeks

Our technical support team provides comprehensive assistance including:

• Formulation guidance and compatibility testing
• Regulatory support for different markets
• Stability testing protocols and assistance
• Claims support with clinical data references
• Custom development for specific application needs

Ready to enhance your formulations with premium Hydroxypinacolone Retinoate?

Contact our technical specialists today to discuss your specific requirements, request samples, or obtain detailed technical documentation.

Please include in your inquiry:

• Your company information and intended applications
• Required quantity and specifications
• Any specific customization needs
• Target markets and regulatory requirements

We respond to all inquiries within 24 business hours and are committed to building long-term partnerships through superior products and technical support.