NK-L1002 Nanoencapsulated 4-butylresorcinol Cosmetic raw materials
INCI No. : Butylene Glycol / Tocopherol / 4-Butylresorcinol / Phospholipids / Caprylic/capric Triglyceride / Polysorbate 80 / Methylparaben / AQUA
Place of Origin: Guangdong, China
Usage: Cosmetic Raw Materials, Anti-aging products, Moisturizers, Skin Repair Products,Sunscreen products
Product Names: NK-L1002 Nanoencapsulated 4-butylresorcinol
Appearance: Light yellow to yellow transparent viscous liquid
Brand Name: NIKOO
Model Number: NK-L1002
Grade: Comestic Grade
Packaging Details: 1kg/bottle, 10kg/can
Product Characteristics
4-Butylresorcinol (English name: 4-Butylresorcinol, CAS No.: 18979-61-8, molecular formula: C10H14O2, molecular weight: 166.22) is a highly effective human complex enzyme inhibitor, which can inhibit melanogenesis, and can inhibit two enzymes necessary for melanogenesis, namely tyrosinase and 5,6-dihydroxyindole-2-carboxylate-oxidase. -Among resorcinol derivatives, 4-butylresorcinol is the most potent in in vitro and in vivo studies.
In the three processes of melanin formation in human skin, 4-butylresorcinol not only has an important inhibitory effect on tyrosinase activity, but also its whitening activity has a synergistic effect in the process.
1, before melanin synthesis, interferes with tyrosinase synthesis and glycosylation, preventing the enzyme from being absorbed by melanosomes.
2, During melanin synthesis, it inhibits the activity of the enzyme, acts as a competitive inhibitor of tyrosinase and TRP1 enzyme, and reduces the formation of by-products that promote melanin production.
3. After melanin synthesis, it increases the degradation of tyrosinase, inhibits the transfer of melanosomes to keratinized cells, and has a photo-peeling effect due to the action of fatty acids. This function is enhanced by the presence of fatty acids and regulates the degradation of tyrosinase.
In product application, the phenolic group of 4-butylresorcinol has a strong antioxidant activity, which is easily oxidized in the air and difficult to preserve, making it very easy for consumers to use the product before it is absorbed by the skin and already oxidized and inactive, thus failing to achieve the desired efficacy. 4-butylresorcinol's slightly water-soluble nature makes it difficult to be added to transparent essences, masks, and aqueous preparations.
The stratum corneum of human skin has a strong barrier function, and it is difficult for large molecule efficacy substances to penetrate. Phospholipid liposomes have a double membrane structure, similar to the structure of the biological cell membrane of the skin, and liposomes have high biological affinity with the skin, and it is easier for them to be fused and absorbed by the cell membrane, which makes liposomes easy to be absorbed and penetrated in the epidermis of the skin.
NK-L002 4-butylresorcinol is wrapped in liposome through phospholipid liposome wrapping technology, using phospholipids as the carrier to wrap the water-insoluble 4-butylresorcinol in liposome, after phospholipid liposome wrapping treatment, the performance of the product has been greatly improved and changed:
1. Enhanced the water solubility of the product, making it easy to be used in aqueous essence products.
2, wrapped with 4-butylresorcinol phospholipid liposome and skin bioaffinity is high, enhanced transdermal absorption of the active ingredients, improve bioavailability, so that it can achieve good results in a small concentration.
3. The phospholipid liposome structure has a slow-release effect, thus reducing its irritation to the skin.
Product Specification
|
Item |
Specification |
|
Model No. |
ULA-L1002 |
|
Product Names |
ULA-L1002 Nanoencapsulated 4-butylresorcinol |
|
Appearance(25℃) |
light yellow to yellow transparent viscous liquid |
|
Smell |
Slightly characteristic odor |
|
Total number of bacterial colonies |
≤200 cfu/ml |
|
Total number of molds and yeasts |
≤100 cfu/ml |
|
PH Value(10% aqueous solution, 25℃) |
4.5-6.5(2% aqueous solution) |
|
HEAVY METAL(PPM) |
<10 |
|
Arsenic (chemistry) |
<2ppm |
|
Active substance content |
9.5-11.0% |
|
Usage |
Cosmetic Raw Materials, Anti-aging products, Moisturizers, Skin Repair Products,Sunscreen products |
Product Application
Product efficacy
NK-L002 Package 4-Butylresorcinol is an efficient skin whitening and brightening agent in cosmetic industry applications with the following effects:
1, It has strong strong inhibition effect on tyrosinase and peroxidase (chemical) enzyme;
2, It can be used as an effective skin whitening and brightening agent with normal skin toner in daily care products;
2, It can be used as an effective skin whitening agent for pigmented skin;
3, can effectively fight against melasma (skin with excessive pigmentation exposed to sunlight);
4, It has a strong protective effect on peroxide-induced DNA damage;
5, proved to have anti-glycation effect.
Applications
1, whitening cream emulsion products;
2, whitening essence, liquid, masks and other water-based products.
Packaging
1kg/bottle, 10kg/tank according to customers' requirements
For samples, it is shipped by express , such as FedEx,DHL,TNT& UPS, it takes around 3-7 days. For bulk order, we will recommend to ship by sea. If you have cooperated shipping agent in China , we can ship to their warehouse for you.
1, the addition amount of 1.0%-10.0% or so, it is recommended that the product is added in the formulation of low temperature (below 55 ℃ when) stage;
2、It is recommended that its package is light-avoidance closed package to reduce contact with air and light sources, sealed storage, and pay attention to reasonable sun protection.
Storage: room temperature (5-25 ℃) to save sealed, shaded cool place to save, 4-5 ℃ refrigeration is preferred. After opening, wipe the bottle clean and store it in airtight refrigerated storage, it is recommended to use it up within 1 month after opening.
Shelf life: the product can remain stable for at least two years when stored in closed containers under the recommended conditions.
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