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NIKOO Chemical - Skincare Raw Material Supply and Custom Solution Specialist for 15 years. 

NK‑023 Yeast Ferment Lysate Filtrate – The Multi‑Functional Postbiotic for Brightening, Hydration & Skin Resilience

A 99% pure, ready‑to‑use filtrate derived from Saccharomyces fermentation – rich in bioactive lysate components. Clinically proven to whiten, soothe, hydrate, fight free radicals, and inhibit C. acnes.

NK‑023 Yeast Ferment Lysate Filtrate – The Multi‑Functional Postbiotic for Brightening, Hydration & Skin Resilience 1

Product Overview:
Yeast (Saccharomyces) is a single‑celled fungus that has been used for millennia in fermentation (bread, wine, beer). Beyond food, its application in skincare dates back to ancient Babylon and Greece, where fermented yeast products were used to heal wounds and beautify skin.

NK‑023 is produced by controlled fermentation of Saccharomyces, followed by lysis (cell breakdown) and filtration. The resulting filtrate contains all the active components released from the yeast cells – proteins, nucleic acids, vitamins, minerals, and polysaccharides – without any live microorganisms. It combines the benefits of a ferment filtrate with the rich nutrient profile of a lysate.

Key Benefits at a Glance:
Benefit Mechanism Test Data
✨ Whitening & brightening Inhibits tyrosinase activity – blocks melanin synthesis 92.86% tyrosinase inhibition (100 mg/mL)
⚡ Antioxidant Scavenges free radicals – protects against oxidative stress 43.70% DPPH radical scavenging (neat)
🌿 Anti‑inflammatory Downregulates IL‑8 production – calms irritation Significant IL‑8 reduction (P<0.001)
💧 Deep hydration Rich in natural moisturising factors 21‑108% relative humidity over 24h
🦠 Anti‑acne Natural antimicrobial activity >7 mm inhibition zone against C. acnes
🧴 Sebum balance Regulates excess oil production Helps maintain oil/water balance
🔄 Anti‑aging Improves skin elasticity, smooths fine lines Supports normal skin turnover
Technical Specifications:
Parameter Value
Product code NK‑023
INCI Name Saccharomyces Ferment Lysate Filtrate, Hydroxyacetophenone, 1,2‑Hexanediol
Composition 99% yeast ferment lysate filtrate + 0.5% hydroxyacetophenone + 0.5% 1,2‑hexanediol
Appearance Colorless to pale yellow clear transparent liquid
Odor Characteristic (mild, yeasty)
Solubility Fully water‑soluble
Recommended dosage 1.0 – 77.0% (can be used as a base in many formulas)
Applications Face masks, serums, toners, waterless formulas, anti‑aging creams, acne treatments

Proven Efficacy (in‑vitro):

  • Tyrosinase inhibition: 92.86% at 100 mg/mL – excellent whitening potential (P<0.05).

  • DPPH radical scavenging: 43.70% (neat) – strong antioxidant activity.

  • IL‑8 downregulation: Significant reduction (P<0.001) – confirms anti‑inflammatory/soothing efficacy.

  • Hydration: Relative moisture retention between 21.1% and 107.95% over 24 hours.

  • Antibacterial (against C. acnes): Inhibition zone >7 mm – confirms anti‑acne effect.

Why NK‑023 Stands Out:
✅ Ultra‑high purity – 99% ferment lysate filtrate, minimal preservatives.
✅ Multi‑functional – whitening, antioxidant, anti‑inflammatory, moisturising, anti‑acne, sebum regulation.
✅ Natural & gentle – derived from traditional fermentation, no harsh chemicals.
✅ Versatile – can be used from 1% up to 77%, even as the main water phase.
✅ Scientifically supported – data on tyrosinase, DPPH, IL‑8, hydration, and antibacterial activity.

Formulation Guidelines:

  • Dosage: 1‑77% depending on desired efficacy. For sheet masks and toners, up to 77% can be used as the base.

  • Addition: Add at any stage (heat‑stable up to 80°C). For optimal preservation, add during cool‑down phase.

  • Compatibility: Compatible with most cosmetic ingredients.

  • Applications:

    • Whitening & brightening serums

    • Soothing & anti‑redness toners

    • Anti‑acne gels & spot treatments

    • Hydrating sheet masks

    • Waterless / anhydrous formulations

    • Anti‑aging creams & emulsions

NK‑023 – The yeast postbiotic that brightens, hydrates, soothes, and clears – backed by ancient wisdom and modern science.

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