NIKOO Chemical - Skincare Raw Material Supply and Custom Solution Specialist for 15 years.

NK‑H2011 Multi‑Amino Acid Complex – Biomimetic NMF Replenisher for Deep Hydration & Elasticity

2026-05-12

A scientifically formulated blend of 19 amino acids, PCA‑Na, betaine, and lactates – mimics skin’s natural moisturising factors (NMF). Restores moisture barrier, boosts elasticity, and refines skin texture.

NK‑H2011 Multi‑Amino Acid Complex – Biomimetic NMF Replenisher for Deep Hydration & Elasticity 1

Product Overview:
Human skin’s ideal state is defined by a balanced epidermal oil‑water matrix and a resilient dermal elastic network. NK‑H2011 is developed under biomimetic theory, referencing advanced Japanese, Korean, and European cosmetic concepts. It replenishes the water‑soluble NMF fraction of the stratum corneum, working in harmony with intercellular lipids. The formula contains:

19 amino acids (glycine, serine, proline, alanine, lysine, arginine, valine, histidine, isoleucine, leucine, aspartic acid, threonine, glutamic acid, cystine, plus others) – building blocks of collagen, elastin, and natural moisturising factors
Betaine (trimethylglycine) – powerful osmotic regulator, retains water in cells
PCA‑Na (sodium PCA) – superior humectant, holds moisture better than glycerin
Sodium lactate & lactic acid – part of natural NMF, forms a hydrating film and gently exfoliates
Allantoin – soothes, calms, and promotes skin repair

This unique combination supplies both intracellular water (active water delivery) and surface hydration, working deeper than conventional hyaluronic acid which mainly sits on the skin surface.

**Key Benefits at a Glance:**
Benefit	Mechanism
💧 Deep, active water replenishment	Amino acids and PCA‑Na penetrate the stratum corneum and bind water inside keratinocytes – not just on the surface
📈 Improves skin elasticity & firmness	Proline, glycine, alanine – key components of collagen and elastin; clinical tests show increased elasticity after 3 weeks
🔄 Restores orderly skin texture	Repairs disordered skin ridges ; after 3 weeks, skin surface becomes more regular and smooth (microscopy confirmed)
🧴 Water‑oil balance	Lactates and NMF components balance hydration without greasiness – comfortable, silky feel
✨ Soothes & repairs	Allantoin reduces irritation; amino acids support barrier recovery
🚫 Non‑sticky, fast absorption	Compared to high glycerin formulas, ULA‑H2011 gives a fresh, silky after‑feel

**Technical Specifications:**
Parameter	Value
Product code	NK‑H2011
INCI complex	Water, Betaine, Sodium PCA, Sodium Lactate, Glycine, Serine, Lactic Acid, Taurine, Proline, Alanine, Lysine, Arginine, Allantoin, Valine, Histidine, Isoleucine, Leucine, Aspartic Acid, Threonine, Glutamic Acid, Cystine
Appearance	Pale to light yellow transparent liquid, slight characteristic odor
pH (as supplied)	5.0 – 6.5
Solids content	33 – 35%
Nitrogen content	4 – 6%
Heavy metals	Pb ≤10 ppm, As ≤1 ppm
Microbial limits	<100 cfu/g; no pathogens
Recommended dosage	0.5 – 10.0%
Applications	Toners, serums, essences, creams, masks, body lotions

Clinical / instrumental data (3‑week human test, n=7, 10% ULA‑H2011 toner, twice daily):

Cornified moisture (Corneometer CM825): significant increase
Skin elasticity (Cutometer MPA580): significant increase
Skin surface morphology (2‑way microscope): disordered skin ridges became clear and well‑structured after 3 weeks – indicating repair of rough, dry texture
TEWL reduction: reduced transepidermal water loss, confirming barrier improvement

Comparison vs. 10% glycerin:

NK‑H2011 gives a fresh, silky, non‑sticky skin feel, while glycerin tends to feel tacky.
NK‑H2011 works inside cells (active water), whereas HA/glycerin mainly hydrate the surface.

Formulation Guidelines:

Dosage: 0.5‑10% (2‑5% for most leave‑on products; up to 10% for intensive serums).
Addition: Heat‑stable; can be added to water phase at any temperature (normal hot process acceptable).
pH range: Stable at pH 4‑9. Avoid extreme pH near isoelectric points of amino acids.
Compatibility notes: Contains electrolytes (PCA‑Na, lactates). May reduce viscosity with conventional carbomers. Use salt‑tolerant thickeners (xanthan gum, Carbomer U series, etc.). Avoid combining with reducing sugars (e.g., sorbitol) under high heat – may cause Maillard browning.
Applications:
- Hydrating & firming toners
- Elasticity‑boosting serums
- Barrier repair creams
- Anti‑aging moisturisers
- Sooth‑and‑repair masks