NK‑L1009 Water‑Soluble Salicyloyl Phytosphingosine – Liposomal Ceramide Precursor for Advanced Barrier & Anti‑Aging
A synergistic derivative of phytosphingosine and salicylic acid – encapsulated in nanoliposomes (50‑100 nm). Boosts ceramide synthesis, reduces inflammation by 70% (IL‑1a), controls oil, and remodels the dermal‑epidermal junction.
Product Overview:
Salicyloyl phytosphingosine is a novel, multifunctional active derived from phytosphingosine (a natural ceramide precursor) and salicylic acid. It combines the barrier‑repairing and antimicrobial properties of phytosphingosine with the exfoliating, anti‑inflammatory, and oil‑controlling benefits of salicylates. However, this active has poor solubility in both water and oils and tends to crystallise, limiting its bioavailability and formulation stability.
NK‑L1009 solves this using phospholipid liposome encapsulation (50‑100 nm particles). The result is a clear, water‑soluble microemulsion that is stable, non‑crystallising, and highly bioavailable. The liposomal structure mimics skin cell membranes, allowing deep penetration and sustained release.
| Benefit | Mechanism / Data |
|---|---|
| 🛡️ Barrier repair | Induces ceramide synthesis; strengthens stratum corneum, reduces TEWL |
| ✨ Anti‑aging & wrinkle reduction | Enhances DEJ (dermal‑epidermal junction) proteins; increases procollagen‑1; reduces MMP‑1 (collagen degradation) |
| 🔥 Anti‑inflammatory | Reduces IL‑1a release by up to 70% – calms redness, swelling, and irritation |
| 🧴 Exfoliation & oil control | Lipophilic salicylate gently dissolves excess sebum and dead skin cells; unclogs pores |
| 🌿 Antimicrobial | Inhibits bacterial growth on the skin – helps with acne and breakouts |
| 💧 Hydration & moisturisation | Promotes natural ceramide production, improving water retention |
| ✨ Whitening & even tone | Inhibits tyrosinase and melanin transfer; reduces post‑inflammatory hyperpigmentation |
| Parameter | Value |
|---|---|
| Product code | NK‑L1009 |
| INCI (principal) | Water, Glycerin, Butylene Glycol, Phosphatidylcholine, PEG‑20 Sorbitan Cocoate, Salicyloyl Phytosphingosine, 1,2‑Hexanediol, Hydroxyacetophenone |
| Appearance | Light yellow to yellow translucent microemulsion |
| Odour | Slight characteristic |
| pH (5% solution) | 6.0 – 9.5 |
| Solubility | Fully water‑soluble (gives clear solution) |
| Active content (salicyloyl phytosphingosine) | 1.0 – 1.3% |
| Particle size | 50 – 100 nm (liposome) |
| Heavy metals | ≤10 ppm (Pb); As ≤2 ppm |
| Microbial limits | <200 cfu/ml; no pathogens |
| Recommended dosage | 1.0 – 10.0% |
| Addition method | Add at <50°C (cool‑down phase) |
| Applications | Serums, toners, masks, creams, lotions, acne treatments, sunscreens, after‑sun repair |
Why Formulators Choose NK‑L1009:
✅ Water‑soluble & transparent – ideal for clear serums and toners.
✅ No crystallisation – stable liposomal dispersion.
✅ High efficacy – 70% reduction in IL‑1a, proven collagen boost, ceramide induction.
✅ Multifunctional – replaces several actives (salicylic acid, ceramides, anti‑inflammatories).
✅ Mild & well‑tolerated – less irritating than free salicylic acid.
Formulation Guidelines:
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Dosage: 1 – 10% (2‑5% for daily anti‑aging/barrier support; 5‑10% for intensive acne/anti‑inflammatory treatment).
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Addition: Add to water phase during cool‑down (<50°C) to preserve liposome integrity.
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Applications:
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Anti‑aging & firming serums
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Barrier repair lotions (for sensitive, eczema‑prone skin)
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Oil‑control & pore‑refining toners
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Acne / blemish spot treatments
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After‑sun calming gels
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Whitening & even‑tone essences
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Packaging & Storage:
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Packaging: 1 kg / bottle, 10 kg / can
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Storage: 5‑25°C, sealed, dark; refrigeration (4‑5°C) recommended after opening
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Shelf life: 2 years unopened
NK‑L1009 – The liposomal ceramide precursor that rebuilds barriers, calms inflammation, and restores youthful skin.
