INCI No. : NONAPEPTIDE-1
Place of Origin: Guangdong, China
Usage: Cosmetic Raw Materials, Anti-aging products, Moisturizers, Skin Repair Products
Product Names: Nonapeptide-1 ,Melanostatine
C61H87N15O9S
Appearance:white powder
Brand Name: NIKOO
Model Number: NONAPEPTIDE-1
Grade: Comestic Grade
Packaging Details:
Product Characteristics
Mechanism of action:
The source of melanin formation in human cells is mainly ultraviolet radiation, which produces various chemical reactions within the skin to generate melanin. Ninapeptide-1 is a whitening active small molecule peptide containing nine amino acids that inhibits melanin formation and reduces hyperpigmentation, and its key target is the MC1R gene outside of the pigmentation cells. The key target of its action is the MC1R gene outside the pigmentation mother cells. Firstly, when the human stratum corneum cells receive UV rays, they release a large amount of α-MSH, which then enters into the deeper layers of the skin and binds to the MC1R receptor on the pigmentation mother cells. Once the two bind, they directly activate a series of reactions within the melanocyte to rapidly produce melanin. Ninhydrin-1 prevents α-MSH from binding to the MC1R receptor and competitively antagonizes the MC1R receptor. When α-MSH reaches the extracellular binding site of the pigmented cells, it will be found that the site has already been occupied by natriuretic peptide-1, so as to reduce the binding of α-MSH to MC1R, and inhibit the production of melanin. Therefore, the whitening method of NNinapeptide-1 is to effectively inhibit the production of melanin from the source so that the skin can be whitened from the bottom to the translucent.
There are two main reasons why Ninhydrin-1 is a whitening active peptide:
1. Ninapeptide-1 inhibits melanin production from the source.
Inhibit the production of melanin from the source, most of the existing whitening ingredients are through the inhibition of tyrosinase activity to inhibit the production of melanin, while the Ninapeptide-1 role in the production of melanin in the source, far before the activation of tyrosinase activity;
2. Safe whitening and spot removal, and at the same time can
Prevent post-inflammatory hyperpigmentation. No irritation, no color change, high stability of the formula.
Product Specification
Item |
Specification |
Model No. |
Nonapeptide-1 |
Product Names |
Nonapeptide-1 ,Melanostatine |
Appearance(25℃) |
White powder |
Smell |
Odorless |
PH Value(10% aqueous solution, 25℃) | 6.0-8.0 |
Azelaic Acid Content
|
≥13% |
Total bacterial cfu/g
|
≤500cfu/g |
Usage |
Cosmetic Raw Materials, Anti-aging products, Moisturizers, Skin Repair Products |
Product Application
Ninapeptide-1 has the efficacy of beauty and light spots, hydrating and moisturizing, repairing scars, etc. It is often used to brighten skin tone and beautify the face.
1、Beauty light spot: Ninapeptide-1 is a kind of bionic peptide. It can be combined with the specificity of melanin cells in the body, effectively prevent and avoid the stimulation of melanin cells, reduce the activity of tyrosinase, so as to reduce the formation of melanin in the body. It is commonly used to lighten pigmentation and brighten skin color, and is widely available in women's skin care products.
2, hydration and moisturizing: Ninapeptide-1 added to skin care products, can effectively hydrolyze sodium hyaluronate, and help skin absorption. Helps to be able to improve the micro-environment of the skin, improve skin roughness, with good hydration and moisturizing effect.
3, repair scars: Ninapeptide-1 in the special ingredients have to promote the degradation of scar tissue collagen polymer, can effectively help the skin to generate new collagen, fast fade scars. At the same time, it reduces the generation of scar tissue, stimulates skin healing, and makes the skin firmer.
In addition, Ninapeptide-1 can also play a role in minimizing fine lines, and has a secondary effect on slowing down the aging process.
Packaging
100g/bag according to customers' requirements
For samples, it is shipped by express , such as FedEx,DHL,TNT& UPS, it takes around 3-7 days. For bulk order, we will recommend to ship by sea. If you have cooperated shipping agent in China , we can ship to their warehouse for you.
It is recommended that its package is light-avoidance closed package to reduce contact with air and light sources, sealed storage, and pay attention to reasonable sun protection.
Storage: room temperature (5-25 ℃) to save sealed, shaded cool place to save, 4-5 ℃ refrigeration is preferred. After opening, wipe the bottle clean and store it in airtight refrigerated storage, it is recommended to use it up within 1 month after opening.
Shelf life: the product can remain stable for at least two years when stored in closed containers under the recommended conditions.
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