98% purity PALMITOYL TETRAPEPTIDE-7 Skincare Raw Material for anti-aging effects, soothing sensitivity, and improving skin elasticity

commonly used in anti-wrinkle and repair skincare products, and is particularly suitable for sensitive and early-aging skin.

Palmitoyl Tetrapeptide-7 is a synthetic peptide ingredient that primarily works by regulating skin inflammation, strengthening the skin barrier, and promoting collagen production, thereby exerting anti-aging effects, soothing sensitivity, and improving skin elasticity. It is commonly used in anti-wrinkle and repair skincare products, and is particularly suitable for sensitive and early-aging skin.

Palmitoyl Tetrapeptide-7 is a high-performance cosmetic peptide renowned for its anti-inflammatory and anti-aging properties.

Key Benefits

• Anti-Aging: By promoting collagen regeneration and inhibiting inflammation, it slows the appearance of dynamic and static lines and improves skin firmness.
• Sensitivity: Reduces redness and burning sensations caused by external irritation or skin barrier damage, improving skin tolerance.
• Improves Elasticity: Long-term use can increase skin's plumpness, leaving it softer and more delicate to the touch.

Palmitoyl Tetrapeptide-7 is synthesized using solid-phase peptide synthesis (SPPS), a reliable and scalable method that ensures high purity and consistency. The process can be summarized as follows:

Resin Activation: The process begins with chlorotrityl chloride (2-CTC) resin as the solid support, which is activated and swollen in a solvent.

Sequential Amino Acid Coupling: The peptide chain is built one amino acid at a time. The sequence involves coupling Fmoc-protected amino acids in the order: Fmoc-Arg(pbf)-OH → Fmoc-Pro-OH → Fmoc-Gln(trt)-OH → Fmoc-Gly-OH. Each coupling step is followed by a deprotection step to remove the Fmoc group and prepare the chain for the next amino acid.

Palmitoylation: After the tetrapeptide chain (GQPR) is assembled, a palmitoyl group is attached to the N-terminus. This lipidation is crucial as it enhances the peptide's ability to penetrate the skin's lipid barrier.

Cleavage and Purification: The finished peptide is cleaved from the resin and simultaneously deprotected using a reagent cocktail. The crude product is then purified, typically by reverse-phase chromatography, and lyophilized to obtain the final pure powder with a purity often exceeding 95%

• Cutting-Edge Manufacturing Facility: Equipped with the latest peptide synthesis and purification equipment adhering to GMP standards.
• Experienced R&D Team: Skilled scientists dedicated to product development and customization to fulfill client requirements.
• Robust Quality Control System: Multi-stage quality inspections ensure batch consistency and reliability.
• Competitive Pricing: Direct factory supply eliminates intermediaries, providing cost-effective pricing without compromising quality.
• Flexible Order Quantities & Customization: Supports a wide range of order sizes and customizable packaging options to suit client needs.

Mechanism of Action

Palmitoyl Tetrapeptide-7 is a bioactive signaling peptide that works through multiple pathways to support skin health:

• Reduces Inflammation: It significantly inhibits the overproduction of the pro-inflammatory cytokine Interleukin-6 (IL-6). In vitro studies show a dose-dependent reduction of IL-6 by up to 40%, and by as much as 86% in UV-damaged skin cells.
  
• Stimulates ECM Production: It promotes the synthesis of key components of the skin's extracellular matrix (ECM), including Type I and IV Collagen, Laminin-V, and Hyaluronic Acid, leading to firmer, more resilient skin.
  
• Strengthens Skin Barrier: By supporting the dermal-epidermal junction and ECM proteins, it helps fortify the skin's structure and enhances its natural repair mechanisms

Key Benefits for Skincare Formulations

• Powerful Anti-Aging: Visibly reduces the depth and quantity of wrinkles by combating inflammatory damage and boosting collagen levels.
  
• Skin Soothing & Anti-Irritant: Ideal for soothing and sensitive skincare products, as it effectively calms inflammation and mitigates reactive responses.
  
• Improves Skin Firmness and Elasticity: By increasing collagen and other matrix proteins, it enhances skin density, tightness, and resilience.
  
• Versatile Application: This ingredient is well-suited for a wide range of premium skincare products, including anti-aging serums, eye creams, moisturizers, and firming treatments

We offer flexible ordering options to meet diverse customer needs:

• Sample Availability: Available in 1g, 10g, and 100g sizes for formulation development

• Minimum Order Quantity (MOQ): 1g for standard material

• Standard Packaging: 1g glass vials with rubber stoppers for optimal preservation

• Customization Options:

1. Different purity grades  (95%, 98%, 99%)
   
2. Customized documentation packages
3. Exclusive rights for large volume orders
4. Private labeling and OEM services

• Lead Times: Samples within 3-5 business days, production quantities in 2-3 weeks

Our technical support team provides comprehensive assistance including:

• Formulation guidance and compatibility testing
• Regulatory support for different markets (EU, USA, ASEAN, etc.)
• Stability testing protocols and assistance
• Claims support with clinical data references
• Custom development for specific application needs

Ready to enhance your formulations with premium Palmitoyl Tetrapeptide-7 ?

Contact our technical specialists today to discuss your specific requirements, request samples, or obtain detailed technical documentation.

Please include in your inquiry:

• Your company information and intended applications
• Required quantity and specifications
• Any specific customization needs
• Target markets and regulatory requirements

We respond to all inquiries within 24 business hours and are committed to building long-term partnerships through superior products and technical support.