Brand Name: NIKOOCHEM
Place of Origin: Guangdong, China
Product Names: Tripeptide-32,Chronolux
Chemical Name: Tripeptide-32,Chronolux
INCI: Tripeptide-32
Molecular formula: C12H21N3O6
Molecular Weight:303.01
Appearance:White to off-white powder
Purity: ≥98 %(HPLC)
Storage:Sealed, dry, and protected from light; often recommended at 2-8°C or -20°C for long term
Shelf Life:24 months in original packaging
Tripeptide-32 – Premium Skincare Raw Material from China
potent bioactive peptide widely recognized in the skincare industry for its ability to promote skin regeneration and repair
Product Overview
Tripeptide-32 helps slow the aging process, reduce the formation of wrinkles, and maintain youthful, healthy-looking skin.
As a star ingredient in cosmetics, tripeptide-32 is commonly used in various skincare products, such as face, neck, and hand care. It can be added to lotions, morning and night creams, eye serums, and other beauty products to help improve skin quality and achieve skincare goals.
Product Characteristics
Advanced Production Process
Our state-of-the-art manufacturing workflow guarantees premium quality Tripeptide-32:
Factory Advantages & Manufacturing Capabilities
Product Characteristics & Performance Benefits
Tripeptide-32 is a synthetic peptide ingredient that works primarily by activating skin cell self-repair mechanisms, regulating circadian rhythm-related gene expression, and strengthening the skin's barrier function. It helps the skin cope with external damage such as UV rays and oxidative stress, reducing collagen loss, delaying photoaging, and promoting nighttime repair, improving fine lines and elasticity.
Mechanism of Action and Core Benefits
By activating core circadian clock genes (such as CLOCK and PER1), tripeptide-32 mimics the skin's natural nighttime repair process, helping cells initiate repair processes more quickly after damage. This mechanism is particularly effective for dull skin and slowed metabolism caused by staying up late and irregular sleep and rest schedules.
Ultraviolet rays (UV) damage collagen and elastin fibers and induce oxidative stress. Tripeptide-32 reduces UV-induced matrix metalloproteinase (MMP) activity, inhibiting collagen degradation, while promoting collagen synthesis by fibroblasts, thereby improving skin firmness.
By neutralizing free radicals and inhibiting inflammatory factors (such as IL-6 and TNF-α), Tripeptide-32 reduces cellular damage caused by oxidative stress, alleviating inflammatory reactions such as redness and sensitivity. It is particularly suitable for sensitive skin or skin affected by environmental pollution.
It promotes the expression of filaggrin and keratin, helping the stratum corneum maintain its normal structure and moisture-binding capacity, reducing transepidermal water loss (TEWL) and improving dryness and roughness.
Applications & Formulation Guidance
Applications in Skincare Products
1) Anti-Aging Products
Core Benefit: Reduces fine lines and wrinkles and improves skin elasticity by enhancing nighttime skin repair.
Combined Ingredients: Often synergized with niacinamide, hyaluronic acid, and vitamin A derivatives to enhance anti-aging effects.
2) Repair Serums/Creams
Application: Targets skin affected by late nights, photoaging, or damaged skin barrier, accelerating epidermal and dermal repair.
Formulation: Mostly used in nighttime care products, leveraging the skin's active metabolic cycle.
3) High-End Technology Products
Due to its high synthesis cost, tripeptide-32 is commonly found in the anti-aging lines of high-end brands such as Estée Lauder's Advanced Night Repair product line (selected versions) and La Mer, focusing on the concept of "biorhythm technology."
Safety and Research Support
Mildness: Peptides have a small molecular weight, good transdermal absorption, and are low in irritation, making them suitable for sensitive skin.
Clinical Data: Some studies have shown that tripeptide-32 at a concentration of 0.01%-0.05% can significantly improve skin barrier function (reducing transepidermal water loss (TEWL)) and collagen synthesis.
Market Product Examples
Estée Lauder Advanced Night Repair Serum (Advanced Repair Synchronicity Enhancer): Claims to regulate the skin's circadian rhythm through tripeptide-32, enhancing nighttime repair.
Future Trends and Limitations
Trend: With the rise of the concept of "biorhythmic skincare," tripeptide-32 may be combined with ingredients such as melatonin and plant rhythm extracts to develop more precise repair products.
Limitations: Peptides are easily inactivated and require stabilization techniques (such as liposome encapsulation). Furthermore, the effectiveness of individual ingredients is limited, requiring combination with other active ingredients.
Formulation Recommendations
Table: Formulation Guidelines for Different Applications
| Product Type | Recommended Usage | Key Benefits | Formulation Tips |
| Face Serums | 0.05-0.1% | Intensive soothing and anti-redness | Incorporate in oil phase; add at low temperature (<40°C) |
| Moisturizers | 0.03-0.07% | Daily prevention, mild calming | Add during cooling phase; ensure pH compatibility |
| Eye Products | 0.04-0.08% | Crow's feet reduction, expression line softening | Combine with soothing agents; ensure gentle formulation |
| Sensitive Skin Products | 0.05-0.1% | Barrier enhancement, irritation reduction | Use in minimalist formulas with few potential irritants |
| Targeted Treatments | 0.07-0.1% | Focused redness reduction and relaxation | Higher concentrations for specific area treatment |
Ordering Information & Customer Support
We offer flexible ordering options to meet diverse customer needs:
Our technical support team provides comprehensive assistance including:
Contact Us for Samples & Technical Information
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