Hexapeptide-9 – Premium Skincare Raw Material,ideal ingredient for advanced anti-wrinkle, firming, and rejuvenating skincare formulations

High Purity & Stability/Anti-Aging/Skin Regeneration/Water Soluble & Highly Compatible

Hexapeptide-9, also known as collidine or collidine, is a polypeptide with the chemical formula C24H38N8O9 and a molecular weight of 582.28 g/mol. Its CAS registration number is 1228371-11-6. It appears as a white powder and is primarily used as a cosmetic ingredient. Composed of six amino acids, its structural characteristics are similar to those of the basement membrane collagens found in human collagens IV and XVII.

As a signal peptide, hexapeptide-9 promotes the synthesis of type I collagen, type IV collagen, laminin-5, and integrins, achieving anti-wrinkle repair effects. It has shown significant effects in reducing facial wrinkles, fading fine lines around the eyes and crow's feet, enhancing skin elasticity, and repairing acne scars.

Product Characteristics

• High Purity & Stability: Manufactured with over 98% purity, ensuring consistent and reliable performance.
• Anti-Aging Benefits: Stimulates collagen production to reduce wrinkles and fine lines, enhancing skin firmness.
• Skin Regeneration: Supports cellular repair and renewal for smoother, younger-looking skin.
• Water Soluble & Highly Compatible: Easily blended into various formulation bases including creams, serums, and lotions without compromising texture or stability.
• Gentle & Safe: Suitable for all skin types, including sensitive skin.

Hexapeptide-9 is a highly effective bioactive peptide renowned in the skincare industry for its powerful anti-aging and skin-regenerating properties. Known for promoting collagen synthesis and supporting skin firmness and elasticity, Hexapeptide-9 is an ideal ingredient for advanced anti-wrinkle, firming, and rejuvenating skincare formulations.

Our manufacturing process employs cutting-edge technology and strict quality control to ensure premium product quality:

• Premium Raw Materials: Selected pharmaceutical-grade raw materials as starting points.
• Peptide Synthesis: Utilizing advanced solid-phase peptide synthesis (SPPS) technology to accurately assemble the peptide chain.
• Purification: Advanced chromatographic methods carefully purify the product to maintain over 98% purity.
• Quality Testing: Rigorous analytical testing such as HPLC and Mass Spectrometry verifies product purity, identity, and safety.
• Secure Packaging: The peptide is packaged in moisture-proof, light-resistant containers to preserve stability during logistics and storage.

• State-of-the-Art Facility: Equipped with modern synthesis and purification systems compliant with international GMP standards.
• Experienced R&D Team: A dedicated team continuously innovates product quality and custom solutions to meet client needs.
• Strict Quality Control: Multiple quality checkpoints throughout the manufacturing process ensure batch-to-batch consistency.
• Competitive Pricing & Direct Supply: Factory-direct sourcing provides cost advantages without sacrificing quality.
• Flexible MOQ & Custom Packaging: We accommodate orders of varying sizes with customizable packaging options.

Mechanism of Action: HEXAPEPTIDE-9 is a bioactive signaling peptide that mimics the body's natural skin repair mechanisms. It works by naturally interacting with skin cells to strengthen structural tissues and promote rejuvenation.

Key Efficacy Claims: It is specifically designed to promote extracellular matrix (ECM) synthesis. This leads to:

• Increased production of Type I and Type IV collagen, laminin-5, and integrin.
• Wrinkle reduction, enhanced skin elasticity, and accelerated wound healing with reduced scar formation.

Target Applications: It is an ideal active ingredient for premium skincare products such as anti-aging serums, repair creams, and treatments for fine lines and wrinkles. A modified version, Cyclohexapeptide-9, has been clinically tested to significantly increase collagen and elastin

Recommended Product Categories

• Sensitive skin treatments for face and body 
• Anti-redness creams and serums for reducing visible redness and inflammation 
• Anti-aging products for preventing and reducing expression lines 
• Post-procedure treatments for calming and soothing after cosmetic procedures
• Barrier repair formulations for enhancing skin resilience 
• Targeted treatments for specific sensitive areas

Formulation Recommendations

Table: Formulation Guidelines for Different Applications

Synergistic Combinations

For enhanced benefits, combine Cyclohexapeptide-9 with:

• Hyaluronic acid for hydration and barrier enhancement 
• Niacinamide for additional barrier improvement and redness reduction
• Antioxidants (Vitamin C, E) for comprehensive protection against environmental stressors 
• Other peptides for multi-mechanism anti-aging action
• Growth factors for enhanced skin rejuvenation and repair

Stability Considerations

To maximize stability and performance in formulations:

• Maintain pH between 5.0-7.0 for optimal stability
• Avoid prolonged heating above 40°C during manufacturing
• Use appropriate preservatives in aqueous systems
• Consider encapsulation for enhanced stability in challenging systems
• Package in airless containers with UV protection to preserve efficacy

We offer flexible ordering options to meet diverse customer needs:

• Sample Availability: Available in 1g, 10g, and 100g sizes for formulation development

• Minimum Order Quantity (MOQ): 1g for standard material

• Standard Packaging: 1g glass vials with rubber stoppers for optimal preservation

• Customization Options:

1. Different purity grades  (95%, 98%, 99%)
   
2. Customized documentation packages
3. Exclusive rights for large volume orders
4. Private labeling and OEM services

• Lead Times: Samples within 3-5 business days, production quantities in 2-3 weeks

Our technical support team provides comprehensive assistance including:

• Formulation guidance and compatibility testing
• Regulatory support for different markets (EU, USA, ASEAN, etc.)
• Stability testing protocols and assistance
• Claims support with clinical data references
• Custom development for specific application needs

Ready to enhance your formulations with premium Cyclohexapeptide-9 ?

Contact our technical specialists today to discuss your specific requirements, request samples, or obtain detailed technical documentation.

Please include in your inquiry:

• Your company information and intended applications
• Required quantity and specifications
• Any specific customization needs
• Target markets and regulatory requirements

We respond to all inquiries within 24 business hours and are committed to building long-term partnerships through superior products and technical support.