loading

NIKOO Chemical - Skincare Raw Material Supply and Custom Solution Specialist for 15 years. 

Nourishing Skin with Oil, a Different Kind of Fermentation | Bumblebee Candida Bombicola + Saccharomyces Cerevisiae Dual-Strain Biotransformation

Our Process: Dual-Strain Fermentation Regulation

— The Wisdom of Microorganisms, Revitalizing Plant Oils for a Light and Rejuvenating Feel —

— Deconstructing a Heavy Body, Creating a Light and Velvety Skin Feel —

Nourishing Skin with Oil, a Different Kind of Fermentation | Bumblebee Candida Bombicola + Saccharomyces Cerevisiae Dual-Strain Biotransformation 1

"Biliary-strain biotransformation of Bumblebee Candida Bombicola + Saccharomyces Cerevisiae" is a bioengineering technology that utilizes the functional complementarity of two yeasts to achieve specific substrate transformation and product synthesis through synergistic or stepwise actions. The core is to leverage the metabolic advantages of the two strains to improve transformation efficiency or expand product types.

1. Core Functional Characteristics of the Two Strains


The value of the dual-strain system is based on the unique metabolic capabilities of both, with the following specific differences:

Strain Name Core Metabolic Characteristics Key Application Directions
Bumblebee Candida bombicola

1. Proficient in synthesizing glycolipid surfactants (such as sophorolipids), possessing biocompatibility and biodegradability;

2. Able to utilize multiple carbon sources (glucose, plant oils, etc.);

3. Some strains can transform steroids, polyphenols, and other active substances.

Surfactant production, active ingredient modification, and oil degradation.
Saccharomyces cerevisiae

1. A classic fermentation strain, efficiently metabolizing sugars to produce ethanol, CO₂, or synthesizing enzymes (such as sucrase) and vitamins;

2. Highly resistant to adverse conditions (tolerant to high sugar levels, with some acid tolerance);

3. Clear metabolic pathway, easily genetically modified.

Food fermentation, enzyme preparation production, substrate pretreatment (e.g., decomposition of complex polysaccharides)

2. Core Mechanisms of Dual-Strain Biotransformation

By "division of labor and cooperation," the metabolic deficiencies of a single strain are compensated for. Two common models are:

Synergistic Transformation (Synchronous Action): Two strains are cultured simultaneously, sharing substrates or metabolic intermediates.

Example: Saccharomyces cerevisiae breaks down cellulose in straw into glucose (producing cellulase), which is then used by Candida albicans to synthesize high-value-added sophorolipids (Candida albicans alone cannot directly utilize cellulose).

Stepwise Transformation (Sequential Action): One strain pretreats the substrate or synthesizes a precursor before inoculating with a second strain to complete the subsequent transformation.

Example: Saccharomyces cerevisiae ferments plant materials to produce phenolic precursors; then Candida albicans is inoculated, and its specific enzyme system modifies the precursors into more active polyphenol derivatives (such as hydroxylated products with higher antioxidant properties).

Fermented Grape Seed Oil

— Bumblebee Candida + Saccharomyces cerevisiae dual-strain biotransformation —

Nourishing Skin with Oil, a Different Kind of Fermentation | Bumblebee Candida Bombicola + Saccharomyces Cerevisiae Dual-Strain Biotransformation 2


INCI:CANDIDA BOMBICOLA/GLUCOSE/METHYL RAPESEEDATE FERMENT, VITIS VINIFERA SEED OIL, CHRYSANTHELLUM INDICUM EXTRACT

  • Appearance: Pale yellow to yellow transparent liquid
  • Recommended Dosage: Dosage can be selected according to cosmetic formulation
  • Efficacy and Skin Feel: Has anti-inflammatory, soothing, and antioxidant effects; feels light and adherent to the skin, with a light, velvety sensation
  • Natural Source: All ingredients are 100% derived from plants (oils) or microorganisms (fermentation products), 100% natural ingredients (100% natural)
  • The maximum addition level of fermented grape seed oil is 51%.

Fermented Sunflower Seed Oil

— Bioconversion by Bumblebee Candida albicans + Saccharomyces cerevisiae—

Nourishing Skin with Oil, a Different Kind of Fermentation | Bumblebee Candida Bombicola + Saccharomyces Cerevisiae Dual-Strain Biotransformation 3

INCI:CANDIDA BOMBICOLA/GLUCOSE/METHYL RAPESEEDATE FERMENT, HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL, CHRYSANTHELLUM INDICUM EXTRACT

  • Appearance: Pale yellow to yellow viscous transparent liquid
  • Recommended Dosage: Dosage can be selected according to cosmetic formulations
  • Efficacy and Skin Feel: A highly hydrating facial and body oil with low viscosity and strong moisturizing effect. Provides a unique texture. Contains active ingredients and is a penetrating facial oil with skin-protecting benefits, etc.
  • Natural Source: All ingredients are derived from plants (oils) or microorganisms (fermentations). 100% natural ingredients (100% natural)

Fermented Camellia Seed Oil

—Bacterial Transformation of Bumblebee Candida albicans and Saccharomyces cerevisiae—

Nourishing Skin with Oil, a Different Kind of Fermentation | Bumblebee Candida Bombicola + Saccharomyces Cerevisiae Dual-Strain Biotransformation 4

INCI:CANDIDA BOMBICOLA/GLUCOSE/METHYL RAPESEEDATE FERMENT, HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL, CHRYSANTHELLUM INDICUM EXTRACT

  • Appearance: Pale yellow to yellow viscous transparent liquid / Pale yellow to yellow viscous transparent liquid microemulsion
  • Recommended Dosage: Dosage can be selected according to cosmetic formulations
  • Efficacy and Skin Feel: A highly hydrating facial and body oil with low viscosity and strong moisturizing effect. Provides a unique texture. Contains active ingredients and is a penetrating facial oil with skin-protecting benefits, etc.
  • Natural Source: 

    100% Natural Ingredients (100% Natural) Suitable for vegan certification.

    All ingredients are derived from plants (oils) or microorganisms (ferments).

prev
Unveiling the New Darling of the Beauty Lab! 5D Polysaccharides
recommended for you
no data
Get in touch with us
Contact Us
Copyright © 2025 Guangzhou Nikoo Chemical Co.,Ltd | Sitemap
Contact us
phone
email
wechat
skype
whatsapp
messenger
Contact customer service
Contact us
phone
email
wechat
skype
whatsapp
messenger
cancel
Customer service
detect