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NIKOO Chemical - Skincare Raw Material Supply and Custom Solution Specialist for 15 years. 

Polydeoxyribonucleotide (PDRN) Promote tissue regeneration, wound healing and anti-aging 1
Polydeoxyribonucleotide (PDRN) Promote tissue regeneration, wound healing and anti-aging 2
Polydeoxyribonucleotide (PDRN) Promote tissue regeneration, wound healing and anti-aging 3
Polydeoxyribonucleotide (PDRN) Promote tissue regeneration, wound healing and anti-aging 1
Polydeoxyribonucleotide (PDRN) Promote tissue regeneration, wound healing and anti-aging 2
Polydeoxyribonucleotide (PDRN) Promote tissue regeneration, wound healing and anti-aging 3

Polydeoxyribonucleotide (PDRN) Promote tissue regeneration, wound healing and anti-aging

INCI No. : PDRN

Place of Origin: Guangdong, China

Usage: Cosmetic Raw Materials, Anti-aging products, Moisturizers, Skin Repair Products

Product Names: Polydeoxyribonucleotide (PDRN)

Appearance:

Brand Name: NIKOO

Model Number: Polydeoxyribonucleotide (PDRN)

Grade: Comestic Grade

Packaging Details

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    Product Characteristics

    Promote tissue regeneration, wound healing

    Anti-inflammatory for acne scars and marks

    Regenerate and anti-wrinkle, age-defying and anti-aging

    Protect cells from UV rays


    PDRN Mechanism of Action.

    • PDRN is a deoxyribonucleic acid mixture derived from a controlled purification and sterilization process of salmon semen DNA (95% similarity to human DNA). This procedure ensures the absence of active proteins and peptides that may cause an immune response.
    • In vitro and in vivo tests have shown that the most relevant mechanism of action of PDRN is the involvement of the adenosine A2A receptor, while PDRN provides nucleosides and nucleotides for the so-called “salvage pathway”, and that binding to the adenosine A2A receptor is a unique property of PDRN.
    • In vitro and in vivo tests have shown that the mechanism of action of PDRN is the involvement of adenosine A2A receptors. PDRN efficiently and specifically activates A2A adenosine receptors on the cell surface, thus promoting the release of cytokines, generating anti-inflammatory effects and repairing damaged cells.
    • The activation of the receptor leads to the proliferation of osteoblasts, fibroblasts, and adipose precursor cells, which activate age-damaged cells and make them more youthful. In addition, VEGF, angiopoietin and glutamine discretionary aminotransferase II are also released with receptor activation, improving blood circulation and accelerating cell renewal.
    • PDRN is found in the human placenta as one of the complexes that generate raw DNA material in cells. It has 95% similarity to human DNA and is free of active proteins and peptides that cause an immune response.
    • PDRN has a special ability to promote recovery after skin grafting and was first used as a tissue repair compound in Italy in 2008 after approval. In recent years, PDRN Mesotherapy has become one of the hottest technologies in Korean skin clinics and plastic surgery due to its miraculous utility in cosmetic surgery. 


    PDRN Benefits.

    • PDRN is a safe substance with no foreign body effects.
    • PDRN increases the skin elasticity of the epidermis and dermis and is heat-stable.
    • Biologically adapted substance made by cutting DNA into specifications.
    • Restores skin damaged by UV rays and skin irritation.



    PDRN 1
    LT2024092701RE (6)
    PDRN 3
    PDRN 4
    PDRN 5
    PDRN 6

    Product Specification

    Item

    Specification

    Model No.

    Polydeoxyribonudeotide (PDRN)

    Product Names

    Polydeoxyribonudeotide (PDRN)

    Appearance(25℃)

    Powder and liquid

    Water soluble

    water soluble

    Additive amount (powder) 0.05%-0.5%
    Additive amount (original liquid, 5000PPM) 1%-10%  
    Thermal stability Stable at 90℃ for 5 minutes
    pH range 5-9 stable, generally stored in 7-8 aqueous solution
    Storage condition ℃-8℃, avoid light
    Shelf life 2years

    Product Application

    • Regeneration and anti-wrinkle: lotions, creams, essences, masks, etc.
    • Remove scars, acne pits, acne marks: functional masks, cold compresses, scar patches, protective gels, lotions, essences, etc.
    • Repair, anti-inflammatory: repair lotion, essence, antibacterial cream, mask, etc.
    • Hair loss prevention: shampoo, lotion, essence, etc., to promote healthy hair follicle tissue regeneration


    Moisturizers-3
    Moisturizers-3
    Anti-aging products-1
    Anti-aging products-1
    Skin Repair Products-4
    Skin Repair Products-4
    Sunscreen products-2
    Sunscreen products-2

    Packaging

    1 g/bottle; 100 g/bottle or according to customers' requirements

    微信图片_20241018165515 (2)
    微信图片_20241018165515 (2)
    微信图片_20241018165521
    微信图片_20241018165521

    For samples, it is shipped by express , such as FedEx,DHL,TNT& UPS, it takes around 3-7 days.  For bulk order, we will recommend to ship by sea.  If you have cooperated shipping agent in China , we can ship to their warehouse for you.


    Shelf life: the product can remain stable for at least two years when stored in closed containers under the recommended conditions.

    faq

    1
    Are you factory or traders?
    YES. We're factory, and accept OEM request, can offer stable raw materials or formula by special requested. We have the advantage of factory's price, as well as the advantage of risk control and responsibility!
    2
    Will you supply samples for test the quality?
    Sure. FREE SAMPLES for collection, we'd like to offer our customers samples for the quality evaluation to develop business.
    3
    What is the MOQ of your product?
    Due to different weight with different products.
    4
    What payment terms are acceptable?
    Any samples please make a easy way for delivery cost translation, regular order T/T payment is the best. But Western Union and Paypal are also acceptable.
    5
    What's your normal delivery time?
    Any samples available immediately . regular order usually lead time 3-5 days, largely order just 1 week lead time.
    6
    Can l get free samples?
    Yes, free sample within 500g, you just pay shipping cost.
    Get in touch with us
    just leave your email or phone number in the contact form so we can send you a free quote for our wide range of designs
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