INCI No. : WATER、TREHALOSE、ARGININE、SODIUM CHLORIDE、1,2-HEXANEDIOL、PENTYLENE GLYCOL、SOLUBLE COLLAGEN
Place of Origin: Guangdong, China
Usage: Cosmetic Raw Materials, Anti-aging products, Moisturizers, Skin Repair Products,Hair Care Products
Product Names: Recombinant Human Type III Collagen
Appearance:
Lyophilized Powder:white or light yellow loose body, after adding sterile deionized water or PBS quickly re-soluble into a clear liquid.
Original Liquid:Clarified liquid.
Brand Name: NIKOO
Model Number: Recombinant Human Type III Collagen
Grade: Comestic Grade
Packaging Details: 1kg/bottle or 100g/bag
Product Characteristics
Collagen type III is a major fibrillar collagen that is found in extensible connective tissues such as skin, lung, and the vascular system. Recombinant human collagen type III α1 / COL3A1 has a long, inflexible, triple-helical domain and has good biocompatibility. Its functional area has a 164.88° flexible triple helix structure. It is being widely studied for clinical application in vascular endothelium, endometrium, wound, oral mucosa repair and orthopedics.
The collagen in the skin of infants and young children is mainly type III, and the collagen in the skin of young adults and the elderly is mainly type I.
Type I collagen determines skin contour support, while type III collagen determines skin elasticity and refinement.
The levels of collagen types I and III are closely related to the skin's youthfulness, trauma repair, cellular support and regeneration, and other behaviors.
Recombinant type III humanized collagen is a type of collagen produced through genetic engineering technology production.
By utilizing its reticulated high polymer structure and hydrophilic properties, it can effectively replenish the deficient collagen in the dermis, fill in and repair the skin barrier, repair damaged elastic fibers within the skin, and promote tissue cell regeneration;
At the same time, it shields the effect of foreign harmful substances, thus relieving and treating various types of problematic skin such as moderate to severe acne symptoms, and truly realizing in-depth skin barrier repair.
The efficacy and function of type III collagen
Skin repair: accelerates protein synthesis, promotes the growth of fiber cells, effectively repairs the base of the muscle, and efficiently repairs!
Firming and anti-wrinkle: replenish collagen, lighten dry lines and fine lines, refine pores and make skin full and moist.
Moisture rejuvenation: Enhance the moisture retention capacity of the stratum corneum to lock the moisture nutrients, so that the skin moisturized exudes vitality, soft and smooth.
The purification method of recombinant human type III collagen by heat treatment of the fermentation broth obtained by the recombinant yeast with the ability to express recombinant human type III collagen under the condition of 65#75℃ effectively prevents the recombinant human type III collagen in the fermentation broth from degrading into small peptides and reduces the production of endotoxin in the fermentation broth, which greatly enhances the purity of recombinant human type III collagen, and improves the purity of recombinant human collagen, and makes skin moisturized and smooth. Collagen purity, to meet the cosmetic raw materials, medical devices and medical grade high-purity collagen; recombinant human type III collagen produced by the method of preparation of recombinant human type III collagen high purity, endotoxin content is low, to meet the cosmetic raw materials, medical devices and medical grade high-purity collagen requirements
Product Specification
Item |
Specification |
Active ingredient |
Recombinant type III humanized collagen |
Function |
Anti-inflammatory and bacteriostatic ,Balance oil clean,Fade print ,Repair barrier |
Appearance(25℃) |
Lyophilized Powder:Appearance is white or light yellow loose body, after adding sterile deionized water or PBS quickly re-soluble into a clear liquid. Original Liquid:Clarified liquid. |
Smell |
Odorless |
PH Value(10% aqueous solution, 25℃) | 6.0-8.0 |
Azelaic Acid Content
|
≥13% |
Total bacterial cfu/g
|
≤500cfu/g |
Adaption symptom |
Whitehead acne, blackhead acne, mild to moderate acne (grade I-II), some moderate to severe acne (grade III-VI), papular acne |
Product Application
Recombinant humanized type III collagen, derived from microorganisms. The product has excellent water solubility and stability, and has good hydrophilic and moisturizing properties, providing a cost-effective recombinant humanized collagen for the development and production of beauty and medical devices. The high expression of yeast and chromatographic purification ensure the purity of the product, and the product does not contain bacterial endotoxin, and the use effect is better.
This product integrates multiple effects such as oil control, acne removal, acne printing, and pore improvement. It is mainly applied to acne skin and other problems. The core ingredient is a two-bottle combination of recombinant type III humanized collagen, white willow extract, quaternary ammonium salt 73 and other ingredients. The recombinant type III humanized collagen extracted by patented technology (100% homology with human body), white willow extract, quaternary ammonium salt 73 and other compound ingredients can penetrate into all levels of skin tissue and be completely absorbed through introduction. It plays the role of anti-inflammation, anti-bacteria, balance oil, improve microenvironment, repair skin lesions, enhance skin barrier, fade color and so on.
Highly active collagen type III for wrinkle reduction and anti-aging
Anti-wrinkle / Anti-wrinkle / Firming / Repairing / Moisturizing
Packaging
1kg/bottle, 100g/bag according to customers' requirements
For samples, it is shipped by express , such as FedEx,DHL,TNT& UPS, it takes around 3-7 days. For bulk order, we will recommend to ship by sea. If you have cooperated shipping agent in China , we can ship to their warehouse for you.
If used for pure type III collagen lyophilized powder recommended additive amount: 10-50%, other types such as emulsions, creams, sprays and other products recommended additive amount: 0.1-5%.
It is recommended that its package is light-avoidance closed package to reduce contact with air and light sources, sealed storage, and pay attention to reasonable sun protection.
Storage: room temperature (5-25 ℃) to save sealed, shaded cool place to save, 4-5 ℃ refrigeration is preferred. After opening, wipe the bottle clean and store it in airtight refrigerated storage, it is recommended to use it up within 1 month after opening.
Shelf life: the product can remain stable for at least two years when stored in closed containers under the recommended conditions.
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