NK-L1004 Water soluble encapsulated ceramide Cosmetic raw materials

Product Characteristics

Ceramides are naturally occurring lipids in the skin that form a water-resistant barrier on the surface of the skin to better protect it and make it moisturized and supple. Among them, ceramide 3 of bio-fermented origin is a new generation of skin moisturizers developed in recent years, which maintains the skin's water retention, repairs dry and damaged skin, and also promotes the renewal of the skin's natural protective layer. It is now widely used as an effective skin care active ingredient in skin care cosmetics.

An important prerequisite for the realization of skin care efficacy is that the active ingredient can effectively penetrate the skin surface, and in the skin tissue, high concentration of enrichment and long retention, that is to say, to achieve the target delivery of skin care active ingredients. Currently, most of the commercially available ceramide cosmetic dosage forms are ordinary creams, with poor skin permeability and retention of the active ingredients.

The active ingredients have poor skin permeability and low retention. At the same time, ceramide 3 is a highly crystalline substance, poorly dispersed in water and most oil esters, with extremely low solubility, and prone to crystallization and precipitation during placement, which is not conducive to the absorption of the active ingredient and the stability of the product.

The stratum corneum of human skin has strong barrier function, it is difficult for large molecule efficacy substances to penetrate, liposome has a double-layer membrane structure, similar to the structure of biological cell membrane of the skin, liposome has high biological affinity with the skin, it is easier to be absorbed by the fusion of the cell membrane, which makes liposome easy to be absorbed in the epidermis of the skin and penetrate.

NK-L1004 encapsulated ceramide is a phospholipid liposome encapsulation technology utilized by NIKOO to encapsulate ceramide 3, which is insoluble in oil esters and water, in liposomes by using phospholipid liposome encapsulation technology, and then use a special process to make liposome ceramide liposomes into transparent microemulsions with particle sizes ranging from 100 to 200 nanometers. The encapsulated ceramide can be directly applied to aqueous products, and it is stable and does not precipitate. At the same time, it is easier to penetrate and absorb the ceramide in the skin epidermis with nanometer phospholipid liposome as the carrier.