Acetyl Tetrapeptide-2 - Premium Anti-Aging and Deodorant Peptide Active

Next-Generation Dual-Action Peptide for Advanced Skincare Formulations

Our Acetyl Tetrapeptide-2 (INCI: Acetyl Tetrapeptide-2, CAS: 757942-88-4), also known as Ac-KDVY-OH, is a high-purity, bioactive peptide that represents cutting-edge innovation in dual-function skincare technology. it offers dual biological activity by simultaneously addressing anti-aging concerns and body odor prevention without causing irritation.  Our Acetyl Tetrapeptide-2 is specially engineered for formulators seeking to create high-performance skincare products that deliver visible anti-aging results within 28 days while providing effective odor control, even for consumers with sensitive skin .

With its unique molecular structure that features an acetyl group attached to the Lys-Asp-Val-Tyr tetrapeptide sequence, our Acetyl Tetrapeptide-2 provides superior efficacy, enhanced skin penetration, and prolonged activity in cosmetic formulations, making it the ideal choice for brands targeting consumers who seek comprehensive skincare solutions without compromising on performance

Our Acetyl Tetrapeptide-2 is manufactured through a proprietary peptide synthesis technology that combines traditional solid-phase peptide chemistry with advanced purification techniques:

• Solid-Phase Peptide Synthesis (SPPS): We utilize Fmoc (fluorenylmethyloxycarbonyl) chemistry-based SPPS methods, which allow for precise control over the sequential addition of amino acids (Lys-Asp-Val-Tyr) to the growing peptide chain on a solid support resin .
• Acetylation Process: Following complete assembly of the tetrapeptide sequence, we perform a specialized acetylation reaction at the N-terminus using acetic anhydride or acetyl chloride under controlled conditions to enhance the peptide's stability and bioactivity .
• Cleavage and Deprotection: The fully assembled and acetylated peptide is cleaved from the resin support while simultaneously removing side-chain protecting groups using a tailored cleavage cocktail, typically containing trifluoroacetic acid (TFA) and appropriate scavengers .
• Purification and Isolation: The crude peptide undergoes multi-stage purification using preparative reverse-phase high-performance liquid chromatography (RP-HPLC) with C18 columns. This process ensures the removal of impurities while maintaining the structural integrity of the peptide molecules .
• Lyophilization: The purified peptide solution undergoes freeze-drying to obtain the final powder form. The lyophilization process is carefully controlled to maintain peptide stability and ensure consistent performance in final formulations
• Comprehensive Quality Control: Each batch undergoes rigorous analytical testing including HPLC for purity assessment, mass spectrometry for identity confirmation, amino acid analysis for composition verification, and stability testing under various conditions to ensure compliance with stringent quality standards

As a leading manufacturer of advanced skincare active ingredients, we offer distinct advantages that make us the preferred partner for skincare brands worldwide:

• Proprietary Synthesis Technology: Our advanced peptide synthesis platform enables production of Acetyl Tetrapeptide-2 with exceptional purity (≥98%) and batch-to-batch consistency, overcoming traditional peptide synthesis challenges 
  
• Significant Production Capacity: With large-scale production facilities and fully automated synthesis systems, we can reliably supply both small development quantities (from 1g) and large commercial volumes (kg scale) with consistent quality .
  
• Customization Flexibility: We offer Acetyl Tetrapeptide-2 in various purity grades (95%, 98%, 99%) and can provide custom formulations tailored to specific application needs 

Our Acetyl Tetrapeptide-2 offers exceptional performance characteristics that make it ideal for advanced skincare formulations:

Dual-Action Benefits

Acetyl Tetrapeptide-2 provides unique dual functionality that addresses both anti-aging concerns and body odor prevention:

• Anti-aging effects: Stimulates collagen synthesis, enhances skin elasticity, and reduces appearance of wrinkles and fine lines 
• Deodorant properties: Neutralizes compounds responsible for aging-related body odor, particularly 2-nonenal 

Anti-Aging Mechanism

The peptide demonstrates significant collagen production capabilities by promoting the synthesis of collagen types I and III in the dermal layer. Clinical studies show visible improvement in skin elasticity and firmness with regular use

Deodorant Mechanism

Acetyl Tetrapeptide-2 works through a sophisticated approach to odor control:

• Neutralizes 2-nonenal: Specifically targets and neutralizes 2-nonenal, the compound responsible for characteristic "aging odor" 
• Reduces lipid peroxidation: Helps prevent the lipid peroxidation processes that generate malodorous compounds 
• Antioxidant protection: Provides antioxidant benefits that help prevent the formation of odor-causing compounds

Multi-Action Benefits

Beyond its primary functions, Acetyl Tetrapeptide-2 provides comprehensive skincare benefits:

• Reduces appearance of fine lines and wrinkles by improving skin density and thickness 
• Enhances skin repair processes by accelerating cellular regeneration 
• Improves skin brightness and radiance by promoting healthier skin quality 
• Increases resistance to environmental damage by strengthening the skin's natural structure 
• Provides preventive anti-aging benefits when used regularly 

Enhanced Safety Profile

Unlike some active ingredients, our Palmitoyl Hexapeptide-12 offers:

• Non-irritating application through topical formulations
• Excellent tolerance even for sensitive skin types
• No recovery time or associated procedure risks
• Suitable for long-term use without safety concerns 

Formulation Versatility

Our Acetyl Tetrapeptide-2 is compatible with various formulation systems including:

• Water-based serums and solutions
• Oil-in-water and water-in-oil emulsions
• Advanced delivery systems for enhanced penetration
• Various cosmetic formulations including creams, lotions, and serums 

Excellent Stability

Rigorous stability testing confirms that our Acetyl Tetrapeptide-2 maintains consistent purity and performance when stored under recommended conditions (2-8°C, protected from light) and formulated in appropriate systems

Our Acetyl Tetrapeptide-2 is suitable for a wide range of skincare applications:

Recommended Product Categories

• Anti-aging creams and serums for face and neck 
• Deodorant and odor-control products 
• Body lotions and moisturizers with anti-aging benefits 
• Neck and décolletage creams for comprehensive care 
• Targeted treatments for specific aging concerns 

Formulation Recommendations

Table: Formulation Guidelines for Different Applications

Synergistic Combinations

For enhanced benefits, combine Acetyl Tetrapeptide-2 with:

• Other anti-aging peptides (Matrixyl, Argireline) for multi-mechanism action 
• Hyaluronic acid for hydration and plumping effects 
• Antioxidants (Vitamin C, E) for comprehensive protection 
• Niacinamide for barrier improvement and brightness 
• Growth factors for enhanced skin rejuvenation 

Stability Considerations

To maximize stability and performance in formulations:

• Maintain pH between 5.0-7.0 for optimal stability
• Avoid prolonged heating above 40°C during manufacturing
• Use appropriate preservatives in aqueous systems
• Consider encapsulation for enhanced stability in challenging systems
• Package in airless containers with UV protection to preserve efficacy

We offer flexible ordering options to meet diverse customer needs:

• Sample Availability: Available in 1g, 10g, and 100g sizes for formulation development

• Minimum Order Quantity (MOQ): 1g for standard material

• Standard Packaging: 1g glass vials with rubber stoppers for optimal preservation

• Customization Options:

1. Different purity grades  (95%, 98%, 99%)
   
2. Customized documentation packages
3. Exclusive rights for large volume orders
4. Private labeling and OEM services

• Lead Times: Samples within 3-5 business days, production quantities in 2-3 weeks

Our technical support team provides comprehensive assistance including:

• Formulation guidance and compatibility testing
• Regulatory support for different markets (EU, USA, ASEAN, etc.)
• Stability testing protocols and assistance
• Claims support with clinical data references
• Custom development for specific application needs

Ready to enhance your formulations with premium Acetyl Tetrapeptide-2?

Contact our technical specialists today to discuss your specific requirements, request samples, or obtain detailed technical documentation.

Please include in your inquiry:

• Your company information and intended applications
• Required quantity and specifications
• Any specific customization needs
• Target markets and regulatory requirements

We respond to all inquiries within 24 business hours and are committed to building long-term partnerships through superior products and technical support.