The "Foundation" of Skin | Recombinant Humanized Type I Collagen

Functions of Type I Collagen

Type I collagen has multiple functions in the human body. First, it maintains structural stability. In the skin, the presence of type I collagen supports and strengthens tissue structure, making the skin firm and elastic. It is also a major component of bones, giving them strength and durability.

Second, type I collagen plays a crucial role in wound healing. When the skin is injured or damaged, type I collagen forms fibrous scar tissue at the wound site, filling damaged tissue and promoting wound healing. It also stimulates the formation of new blood vessels, providing more oxygen and nutrients to the wound and accelerating the repair process.

Furthermore, type I collagen provides support at the cellular level. It can build a cell support matrix, serving as a platform for cell attachment and communication, providing a suitable environment for cell growth and expansion. This is essential for normal cell function and development.

1. Type I Collagen in the Skin

Type I collagen plays a vital role in the skin. It constitutes the majority of the protein composition of the skin and is also a major structural protein of the skin. Skin is the largest organ in the human body, protecting internal organs from external damage and playing a crucial role in regulating body temperature and maintaining water balance.

Type I collagen, through its unique molecular structure, provides skin with elasticity and suppleness. It makes skin firm and elastic, reducing wrinkles and sagging. As we age, the amount of type I collagen gradually decreases, leading to loss of skin elasticity, wrinkles, and sagging. Therefore, many skincare products and cosmetic surgeries use type I collagen to improve skin appearance and texture.

2. Type I Collagen in Bones

Besides skin, type I collagen also plays a vital role in bones. Bones are the body's support system, providing structure and protecting internal organs. Type I collagen is a major component of bone tissue, accounting for over 90% of bone mass.

It forms fibrous structures that connect countless tiny particles in the bone, giving it strength and durability. Furthermore, type I collagen attracts and retains calcium ions, making bones stronger and more stable. When a fracture occurs, type I collagen plays a crucial role at the wound site, aiding in fracture healing and bone reconstruction.

3. Type I Collagen in Blood Vessels and Internal Organs

Besides its distribution in the skin and bones, type I collagen is also widely present in the body's blood vessels and internal organ tissues. In blood vessels, type I collagen, along with other proteins, forms the structural framework of the vessel walls, maintaining the shape and stability of the vessels. It also increases the flexibility and elasticity of blood vessels, enabling them to withstand the continuous pressure from the heart.

Applications of Type I Collagen

1. Clinical Uses

Type I collagen has wide applications in the medical field. It is used clinically to treat wound healing, trauma repair, and fracture healing. Because type I collagen can help cell proliferation and tissue regeneration, doctors often use collagen preparations after surgery to promote wound healing. Furthermore, in the treatment of certain diseases, type I collagen is also used as an adjunct to medications or treatments.

2. Applications in Cosmetic and Plastic Surgery

Type I collagen is also widely used in cosmetic and plastic surgery. Many cosmetic surgeries use type I collagen to fill wrinkles, sculpt facial contours, and lift facial lines. This application is very popular in the anti-aging and cosmetic surgery fields because type I collagen provides natural results and is a component of the human body, reducing discomfort and risks associated with surgery.

Experiments with type I collagen