Aloe vera gel, extracted from the plant’s inner leaf, contains over 75 bioactive compounds—polysaccharides, enzymes, and minerals—that deliver reparative and calming effects.
1. Wound Healing Acceleration
Aloe stimulates fibroblast proliferation and collagen synthesis via:
Glucomannan (a polysaccharide) binding to growth factor receptors.
Bradykinase reducing inflammation and pain.
Clinical evidence shows it cuts burn healing time by 30% compared to standard care.
2. Intense Hydration & Barrier Repair
Mucopolysaccharides in aloe form occlusive films on the skin, reducing TEWL. It also enhances aquaporin-3 function—channels regulating water transport—boosting moisture retention in the epidermis.
3. Anti-Inflammatory Action
Salicylic acid and carboxypeptidase inhibit prostaglandin synthesis.
Magnesium lactate blocks histamine pathways, alleviating itchiness.
This makes it effective for psoriasis, eczema, and insect bites.
4. Acne & Hyperpigmentation Control
Antimicrobial lipids (e.g., acemannan) kill C. acnes bacteria.
Aloesin inhibits tyrosinase by 40%, rivaling kojic acid in fading post-inflammatory marks.
5. UV Damage Recovery
Aloe’s glycoproteins reduce UV-induced interleukin-6 (IL-6) production, mitigating redness and DNA damage. When applied post-sun exposure, it lowers skin temperature and accelerates peeling resolution.
Practical Uses
Pure gel: For burns, post-procedure redness, or as a moisturizing mask.
Formulated products: Seek stabilized extracts in serums/creams (0.5–2% concentration).
Caution: Latex (yellow sap near the leaf rind) is a laxative and irritant—use inner-leaf gel only.
Limitations: Degrades rapidly when exposed to air/light; stabilized emulsions outperform DIY preparations.
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