Conotoxin for instant wrinkle elimination of beauty and skin care products

Product Characteristics

Conotoxin is small molecular polypeptides, mostly cysteine-rich, with a highly conserved disulfide bond backbone that allows them to form a highly restricted stereoscopic conformation. Conotoxin was originally isolated from the fish-eating conotyledon Cgeographus. These small peptides are about 17-26 amino acid residues in length and contain 6 cysteines belonging to the M-superfamily of coniferyl peptides. Their spatial structure is more stable and ordered, and their permeability is superior to that of linear peptides, specifically blocking voltage-gated sodium channels and inhibiting muscle contraction.

Muscle contraction is caused by acetylcholine released by nerves. Facial skin is characterized by strong muscle contraction, which results in expression lines, such as headlines, crow's feet, and vertical folds between the eyes. Conotoxin can block the nerve signaling between the nerves and the muscles to relax the striated muscles, which is superior to the anti-wrinkle effect used in MyoIso. μ-conotoxin peptide, which blocks the neuromuscular current conduction by targeting the voltage-dependent sodium channels, especially the Nav1.4 channels, achieves the effect of effectively relaxing the muscles and minimizing the wrinkles. Because of its direct action on sodium ion channels, the effect is rapid, 30 minutes to take effect, 8 hours after the wrinkle effect slowly disappears.

Conotoxin is known as the Botulinum toxin that can be applied, through the application of Botulinum toxin injection can be achieved, is expected to replace the invasive methods such as injections to remove wrinkles, so as to remove wrinkles more safely and effectively, to avoid invasive products on the human body caused by infections, facial paralysis and other potential hazards of the taro peptide structure through the high degree of folding, the ability to penetrate the strong.

Conotoxin can bind m-nAchR, blocking acetylcholine and m-nAchR binding, but also can specifically block the voltage-gated sodium channel, so that the sodium inward flow of sodium ions is blocked, resulting in muscle action potential can not be formed, the expression muscle can be relaxed, so as to effectively prevent and reduce the wrinkles, can be used as an active ingredient of anti-wrinkle products.