Copper Tripeptide-1 (GHK-Cu) - Premium Anti-Aging Peptide Active

Next-Generation Copper Complex Peptide for Advanced Skincare Formulations

Our Copper Tripeptide-1 (INCI: Copper Tripeptide-1, CAS: 130120-57-9/49557-75-7), also known as GHK-Cu or Blue Copper Peptide, is a high-purity, bioactive copper complex peptide that represents cutting-edge innovation in regenerative skincare technology. it offers targeted biological activity by mimicking the body's natural wound healing and tissue regeneration processes without causing irritation. This makes it significantly more effective and regenerative than conventional approaches . Our Copper Tripeptide-1 is specially engineered for formulators seeking to create high-performance skincare products that deliver visible skin regeneration results within 28 days without causing sensitivity or irritation, even for consumers with sensitive skin .

With its unique molecular structure that features a copper ion chelated to the Gly-His-Lys tripeptide sequence, our Copper Tripeptide-1 provides superior efficacy, enhanced skin penetration, and prolonged activity in cosmetic formulations, making it the ideal choice for brands targeting consumers who seek clinical-grade rejuvenation results without invasive procedures 

Our Copper Tripeptide-1 is manufactured through a proprietary synthesis technology that combines peptide chemistry with advanced copper complexation techniques:

• Peptide Synthesis: We utilize Fmoc-based solid-phase peptide synthesis (SPPS) to create the Gly-His-Lys tripeptide sequence with high precision and purity. This method allows for exact control over the amino acid sequence and minimizes impurities .
• Purification: The crude peptide undergoes multi-stage purification using preparative reverse-phase high-performance liquid chromatography (RP-HPLC) with C18 columns. This process ensures the removal of impurities while maintaining the structural integrity of the peptide molecules .
• Copper Complexation: The purified tripeptide-1 is complexed with high-purity copper ions under carefully controlled pH and temperature conditions to form the stable blue copper-peptide complex. This process ensures optimal chelation and bioavailability .
• Patented One-Pot Synthesis: We employ a proprietary one-pot synthesis method that significantly reduces production steps and improves yield. This innovative approach eliminates multiple purification steps while maintaining high product quality, making it more efficient and cost-effective .
• Crystallization and Drying: The complex undergoes controlled crystallization followed by freeze-drying to obtain the final stable powder form. The lyophilization process is carefully optimized to preserve the integrity and activity of the copper-peptide complex
• Comprehensive Quality Control: Each batch undergoes rigorous analytical testing including HPLC for purity assessment, mass spectrometry for identity confirmation, atomic absorption spectroscopy for copper content analysis, and stability testing under various conditions to ensure compliance with stringent quality standards

As a leading manufacturer of advanced skincare active ingredients, we offer distinct advantages that make us the preferred partner for skincare brands worldwide:

• Proprietary Synthesis Technology: Our advanced peptide synthesis platform enables production of Copper Tripeptide-1 with exceptional purity (≥98-99%) and batch-to-batch consistency, overcoming traditional peptide synthesis challenges .
• Significant Production Capacity: With large-scale production facilities and fully automated synthesis systems, we can reliably supply both small development quantities (from 1g) and large commercial volumes (kg scale) with consistent quality .
• State-of-the-Art Equipment: We utilize advanced instrumentation including CS Bio peptide synthesizers, Agilent LC-MS systems, GC-MS, NMR spectrometers, and preparative HPLC systems to ensure precise control over production and quality
• Customization Flexibility: We offer Copper Tripeptide-1 in various purity grades (95%, 98%, 99%) and can provide custom formulations tailored to specific application needs

Our Copper Tripeptide-1 offers exceptional performance characteristics that make it ideal for advanced skincare formulations:

Superior Skin Regeneration

Copper Tripeptide-1 demonstrates significant tissue repair capabilities by promoting the synthesis of collagen, elastin, and other extracellular matrix components in the dermal layer. Clinical studies show visible improvement in skin elasticity and firmness with regular use

Dual Mechanism of Action

The peptide-copper complex works through multiple mechanisms:

• Stimulates collagen production: Promotes synthesis of collagen types I, III, and IV for improved skin structure and elasticity 
• Antioxidant protection: Serves as a potent antioxidant that protects skin from oxidative damage and environmental stressors 
• Wound healing acceleration: Enhances tissue repair and regeneration processes at the cellular level

Multi-Action Benefits

Beyond collagen stimulation, Copper Tripeptide-1 provides comprehensive skincare benefits:

• Reduces appearance of fine lines and wrinkles by improving skin density and thickness 
• Enhances skin repair processes by accelerating cellular regeneration 
• Improves skin brightness and radiance by promoting healthier skin quality 
• Increases resistance to environmental damage by strengthening the skin's natural structure 
• Provides antioxidant protection against free radical damage 

Hair Growth Stimulation

Research demonstrates that Copper Tripeptide-1 can stimulate hair follicles and promote hair growth by increasing blood circulation to hair follicles and extending the growth phase of the hair cycle, making it valuable for haircare formulations 

Enhanced Safety Profile

Unlike some active ingredients, our Copper Tripeptide-1 offers:

• Non-irritating application through topical formulations
• Excellent tolerance even for sensitive skin types
• No recovery time or associated procedure risks
• Suitable for long-term use without safety concerns 

Formulation Versatility

Our Copper Tripeptide-1 is compatible with various formulation systems including:

• Water-based serums and solutions
• Oil-in-water and water-in-oil emulsions
• Advanced delivery systems for enhanced penetration
• Various cosmetic formulations including creams, lotions, and serums 

Excellent Stability

Rigorous stability testing confirms that our Copper Tripeptide-1 maintains consistent purity and performance when stored under recommended conditions (-20°C, protected from light) and formulated in appropriate systems 

Our Copper Tripeptide-1 is suitable for a wide range of skincare applications:

Recommended Product Categories

• Anti-aging creams and serums for face and neck 
• Wrinkle reduction treatments and night products 
• Eye contour treatments for crow's feet and expression lines 
• Regenerative treatments for post-procedure skin recovery 
• Hair growth stimulants for thinning hair and baldness 
• Targeted treatments for specific aging concerns

Formulation Recommendations

Table: Formulation Guidelines for Different Applications

Synergistic Combinations

For enhanced benefits, combine Copper Tripeptide-1 with:

• Hyaluronic acid for hydration and plumping effects 
• Antioxidants (Vitamin C, E) for comprehensive protection 
• Other peptides for multi-mechanism action 
• Niacinamide for barrier improvement and brightness 
• Growth factors for enhanced skin rejuvenation 

Stability Considerations

To maximize stability and performance in formulations:

• Maintain pH between 5.0-7.0 for optimal stability
• Avoid prolonged heating above 40°C during manufacturing
• Use appropriate preservatives in aqueous systems
• Consider encapsulation for enhanced stability in challenging systems
• Package in airless containers with UV protection to preserve efficacy

We offer flexible ordering options to meet diverse customer needs:

• Sample Availability: Available in 1g, 10g, and 100g sizes for formulation development

• Minimum Order Quantity (MOQ): 1g for standard material

• Standard Packaging: 1g glass vials with rubber stoppers for optimal preservation

• Customization Options:

1. Different purity grades  (95%, 98%, 99%)
   
2. Customized documentation packages
3. Exclusive rights for large volume orders
4. Private labeling and OEM services

• Lead Times: Samples within 3-5 business days, production quantities in 2-3 weeks

Our technical support team provides comprehensive assistance including:

• Formulation guidance and compatibility testing
• Regulatory support for different markets (EU, USA, ASEAN, etc.)
• Stability testing protocols and assistance
• Claims support with clinical data references
• Custom development for specific application needs

Ready to enhance your formulations with premium Copper Tripeptide-1?

Contact our technical specialists today to discuss your specific requirements, request samples, or obtain detailed technical documentation.

Please include in your inquiry:

• Your company information and intended applications
• Required quantity and specifications
• Any specific customization needs
• Target markets and regulatory requirements

We respond to all inquiries within 24 business hours and are committed to building long-term partnerships through superior products and technical support.