PALMITOYL PENTAPEPTIDE-4 for Anti-wrinkle, firming, improving skin tone
INCI No. : PALMITOYL PENTAPEPTIDE-4
Place of Origin: Guangdong, China
Usage: Cosmetic Raw Materials, Anti-aging products, Moisturizers, Skin Repair Products
Product Names: PALMITOYL PENTAPEPTIDE-4
Appearance: white powder
Brand Name: NIKOO
Model Number: PALMITOYL PENTAPEPTIDE-4
Grade: Comestic Grade
Packaging Details:
Product Characteristics
Palmitoyl Pentapeptide-4 (pal-KTTKS), a pentapeptide, was once known as Palmitoyl Pentapeptide-3, also known as Matrixyl. It is widely used in anti-wrinkle skin care, and is used as the main ingredient of anti-wrinkle formulations by many famous foreign cosmetic brands (such as Olay, L'Oreal, Avon, etc.), and can be used as facial care and body care anti-aging, eye repair, face, neck and hand care products.
Effects: Anti-wrinkle, firming, improving skin tone.
Mechanism of action:
Palmitoyl Pentapeptide-4 is a signal peptide, is collagen Ⅰ (Collagen Ⅰ) fragments and palmitic acid (PalmiticAcid) after the combination of the skin more affinity and hydrophilic locking substances, through the action of the dermal fibroblasts, to promote the synthesis of the skin tissue in the collagen type I, II and IV, fibronectin and glycosaminoglycan repair and reconstruction of the extracellular matrix and the epidermal fibroblast, repair and reconstruction of the extracellular matrix and the epidermal fibrosis. Reconstructs the extracellular matrix and the epidermal-dermal junction (DEJ), strengthens connective tissues, increases skin firmness, promotes cellular activity, and reduces the appearance of fine lines on the face. It also improves skin water content and moisturization, resulting in smoother and firmer skin, improved skin tone, and enhanced radiance and clarity.
Actions
(1) Palmitoyl Pentapeptide-4 can promote collagen proliferation and indirectly repair micro-damage of human oral mucosa.
(2) Anti-aging effects. For example, palmitoyl Chemicalbook pentapeptide-4 can prevent and improve gum recession.
(3) Palmitoyl Pentapeptide-4 can promote the proliferation of hyaluronic acid and elastic fibers, and can effectively activate hyaluronic acid synthesis.
Product Specification
|
Item |
Specification |
|
Model No. |
Recombinant mussel mucin |
|
Product Names |
pal-KTTKS |
|
Appearance(25℃) |
white powder |
|
Smell |
Odorless |
| PH Value(10% aqueous solution, 25℃) | 6.0-8.0 |
|
Azelaic Acid Content
|
≥13% |
|
Total bacterial cfu/g
|
≤500cfu/g |
|
Usage |
Cosmetic Raw Materials, Anti-aging products, Moisturizers, Skin Repair Products |
Product Application
Applications
Because of its unique properties, palmitoyl pentapeptide-4 is often used in cosmetics. It can be synthesized into an anti-wrinkle and firming composition with five components, including carnosine peptide, oligopeptide-4, palmitoyl tripeptide-5 and oat kernel extract. The above five components complement each other mechanistically and have synergistic effects, and their overall additive amount in a very low range can play a significant anti-wrinkle wrinkle and firming effect.
Related Research
Although Palmitoyl Pentapeptide-4 has multiple effects, it has poor transdermal properties due to its large molecular weight and negative charge at physiological pH, etc. At the same time, it is difficult for Pal-KTTKS to exert its effects due to the hindering effect of Chemicalbook stratum corneum, decomposition of aminopeptidases in the skin, and removal of microvascular system under the dermis. With the goal of enhancing the transdermal absorption of Pal-KTTKS, solid-phase method was used to synthesize Pal-KTTKS lyophilized powder, and the flexible liposomes of Pal-KTTKS prepared by film dispersion supplemented with high-pressure homogenization technology were screened, which could protect the relevant drugs from being decomposed by enzymes and liquids, increase the cumulative transmittance of the flexible liposomes and the cumulative retention capacity of the flexible liposomes per unit area, and prolong the time of action, so that the efficacy of Pal-KTTKS could be better exerted.
Packaging
100g/bag according to customers' requirements
For samples, it is shipped by express , such as FedEx,DHL,TNT& UPS, it takes around 3-7 days. For bulk order, we will recommend to ship by sea. If you have cooperated shipping agent in China , we can ship to their warehouse for you.
It is recommended that its package is light-avoidance closed package to reduce contact with air and light sources, sealed storage, and pay attention to reasonable sun protection.
Storage: room temperature (5-25 ℃) to save sealed, shaded cool place to save, 4-5 ℃ refrigeration is preferred. After opening, wipe the bottle clean and store it in airtight refrigerated storage, it is recommended to use it up within 1 month after opening.
Shelf life: the product can remain stable for at least two years when stored in closed containers under the recommended conditions.
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