PENTAPEPTIDE-3 Reduces wrinkles on eyes, forehead, neck and abdomen cosmetics

Product Characteristics

Pentapeptide-3 is a peptide that effectively reduces the contraction of facial muscles and increases the alignment of collagen and elastin, which prevents the formation of folds and wrinkles and maintains skin firmness

One of the most visible signs of skin aging is an increase in the number of wrinkles on the face, a process that can occur naturally over time; there are a number of other factors that can lead to the appearance of folds and wrinkles on the face, including frequent and sustained pressure on the facial skin from constant gravitational traction (e.g., during sleep) or repetitive facial movements caused by contraction of the facial expression muscles. It is now well recognized that these conformational changes can be significantly avoided by modulating muscle contraction to achieve improvements in wrinkles. Muscles contract when they receive acetylcholine released from vesicles.

Pentraxin-3 is a modified enhanced stability enkephalin that modulates the release of acetylcholine from neuronal cell cultures, attenuating muscle contraction and thereby reducing wrinkle formation. Pentapeptide-3 is effective in reducing the depth of expression lines caused by facial muscle contraction, especially around the forehead and eyes; Pentapeptide-3 provides a peptide alternative to Argireline-like peptides in a novel way that reduces the mechanism of targeted crease expression; Pentapeptide-3 is capable of removing wrinkles at a deeper level on the forehead or around the eyes.

Pentapeptide-3 mimics the natural mechanism of enkephalin in vitro; it binds to enkephalin receptors on the outside of nerve cells; when bound to the receptor, a conformational change initiates a cascade of reactions within the neuron that leads to reduced neural excitability; the reduced activity, in the nerve cells, reduces the release of acetylcholine, which reduces the expression of contraction of the muscle. This activity translates in vivo into relaxation of muscle contraction and a reduction in expression of wrinkles