Recombinant Human Antiviral Protein: Building a Biologic Shield for Skin Health
In the field of cosmetic ingredients, recombinant human antiviral protein has emerged as a revolutionary component for combating external aggressors through its dual mechanism of ‘precise defence + immune regulation.’ This protein, synthesised using genetic engineering technology, replicates the structure of the human body's natural antiviral factors, enabling it to actively identify and defend against various viruses, bacteria, and pollutants, thereby constructing a biologically mimicked protective system for the skin.
Core Mechanism: A Smart Defence System Derived from the Human Body
The protective efficacy of recombinant human antiviral proteins stems from three biological mechanisms:
1. Virus Adhesion Blocking: Mimicking the structure of human β-defensin-2 (hBD-2), its cationic charge specifically binds to viral surface glycoproteins, preventing viruses such as HPV and HSV from adhering to cell membranes. In vitro experiments show a 92% reduction in viral infection rates;
2. Bacterial membrane damage effect: By inserting into bacterial phospholipid bilayers to form pores, it increases the permeability of cell membranes of pathogenic bacteria such as Escherichia coli and Staphylococcus aureus by 85%, achieving a 99.9% antibacterial rate within 2 hours;
3. Capture of Pollutant Particles: The negatively charged regions on the protein surface can adsorb positively charged pollutants such as PM2.5 and heavy metal ions, forming ‘protective microcapsules.’ Tests show capture rates of 89% and 93% for lead and cadmium, respectively.
Diverse Application Scenarios and Formulation Compatibility
- Daily protection products: Recommended addition rate of 0.05%–0.1% for use in protective sprays, isolation creams, and other products, forming an invisible protective film. When used with hyaluronic acid, moisturising and protective effects are synergistically enhanced by 50%;
- Medical Aesthetics and Repair: At a high concentration of 0.3% in post-operative dressings, it reduces the risk of infection in laser-treated wounds (infection rate decreases from 12% to 2%) while promoting epithelial cell regeneration, shortening healing time by 30%;
- Scalp health management: When combined with zinc pyrithione (ZPT), it targets scalp inflammation caused by Malassezia fungi, increasing the antibacterial rate to 96% and reducing dandruff recurrence by 81%.
In terms of formulation compatibility, this protein remains stable within a pH range of 5.0–8.0 and can synergise with components such as peptides and plant extracts. It is recommended to avoid direct mixing with strong oxidants or heavy metal ions.
