Recombinant Collagen Industry Scale and Development Prospects
In recent years, with the rise of genetic engineering technology, synthetic biology is on the rise, and in the collagen track, companies have entered the game and accelerated the layout.
Recombinant collagen has been widely used in skin care products, medical products, medical devices, toiletries, intimate care, oral care, nasal care and food and many other major health fields, showing its extensive market potential and practical value.
First, the recombinant collagen market size
recombinant type III collagen with its unique advantages in a wide range of applications, market demand is rising year by year, recombinant type III collagen raw materials market size is rapidly expanding.
1. Recombinant Type III Collagen Market Size - Raw Material Side
According to the analysis of Frost & Sullivan's data, from 2020 to 2023, the market size of the raw material side of collagen in China increased from RMB 1.63 billion to RMB 3.14 billion, with a CAGR of up to 24.4%; it is expected that by 2030, the market size of the retail side of collagen in China will increase from RMB 1.63 billion to RMB 3.14 billion. Collagen retail end market size will reach RMB 16.39 billion by 2030.
In 2023, China's recombinant type III collagen raw material end of the market size of RMB 810 million, accounting for 25.9% of the collagen raw material end of the market size; China's recombinant type III collagen raw material end of the market is expected to grow rapidly at a CAGR of 43.5% from 2023 to 2030. The recombinant type III collagen raw material end of the market will reach RMB 10.15 billion by 2030, accounting for 62.0% of the overall market size of the retail end of collagen.
According to Frost & Sullivan data analysis, the global collagen raw material end market size increased from $1,030.8 million to $1,411.5 million in 2020-2023, with a CAGR of 11.0%. And will continue to grow at a CAGR of 15.3%. The global collagen raw material end of the market is expected to reach USD 3,814.8 million by 2030.
From 2020 to 2023, the global recombinant type III collagen raw material end of the market size of up to 101.6% CAGR rapid growth to 146.5 million U.S. dollars, accounting for 10.4% of the collagen raw material end of the market size; is expected to reach 1,586.0 million U.S. dollars by 2030, accounting for 41.6% of the overall market size of collagen raw material end of the market size. The global recombinant type III collagen raw material market size is expected to reach 1,586.0 million US dollars by 2030, accounting for 41.6% of the overall collagen raw material market size.
2、Recombinant Type III Collagen Market Size - Retail
According to Frost & Sullivan's data analysis, from 2020 to 2023, China's collagen retail market size increased from 20.47 billion yuan to 58.42 billion yuan, with a CAGR as high as 41.9%; it is expected that by 2030, the market size of the retail side of the recombinant III collagen market will reach 1,586.0 million US dollars, accounting for 41.6% of the overall collagen raw material market size. The retail market size of collagen in China is expected to reach RMB 269.50 billion by 2030, with a CAGR of 41.9%.
From 2020 to 2023, China's recombinant type III collagen retail end market size grows rapidly at a CAGR of 79.0%. In 2023, China's recombinant type III collagen retail end market size will amount to RMB 20.50 billion, accounting for 35.1% of the collagen retail end market size; it is projected that the recombinant type III collagen retail end market size by 2030 will reach 138.37 billion yuan, accounting for 51.3% of the overall market size of the retail side of collagen.
According to Frost & Sullivan data analysis, the global collagen retail end market size increased from $30,501.9 million to $40,601.5 million from 2020-2023; the global collagen retail end market size is expected to reach $78,371.3 million by 2030.
The global recombinant type III collagen retail end market size grew rapidly at a CAGR of 78.4% from 2020 to 2023. in 2023, the global recombinant type III collagen retail end market size was USD 3,063.8 million; by 2030, the recombinant collagen retail end market size is expected to reach USD 24,312.1 million, with a market size share of 31.0%.
Second, recombinant type III collagen industry driving factors
Technology upgrading, favorable policies, regulatory improvement, demand enhancement, application field expansion, etc. to promote the rapid development of the global and Chinese recombinant collagen, including recombinant type III collagen industry.
1, social attitudes, consumer attitudes change
more purposeful consumption: according to the data released by the National Bureau of Statistics, in the first half of 2024, China's residents of the average propensity to consume 65.6%, down from 68.3% in 2023, in this context, “fine calculation, according to the ability to consume,” has become one of the common consumption behavior patterns. In this context, “fine calculation and consumption according to ability” has become one of the common consumption behavior patterns.
Preference for high-quality products: Under the current rationalization of the consumer market, consumers are increasingly inclined to choose products with high efficacy. According to GFK's survey results, 75% of consumers are willing to pay a higher price for products with a longer life cycle, 71% are willing to buy innovative products that offer good value for money, and 65% are willing to spend more on anti-aging beauty products. In addition, products that enhance satisfaction of use, provide functionality and health value are more popular among consumers, and products with excellent experience can even make consumers willing to pay higher prices. Recombinant collagen products, with their remarkable efficacy, are attracting more and more consumers' attention and choices in skincare, medical aesthetics, health food, and other healthcare sectors.
Strengthening of the “weed” attribute of social platforms: With the large-scale popularization of social sharing and evaluation platforms such as Xiaohongshu, Dianping and Weibo, consumers' decision-making paths and habits are undergoing profound changes. These platforms have not only become an important channel for users to express and share their personal experiences, but have also gradually become a key source of information for consumers when searching for, screening and trusting products and services. According to the “Top 10 Life Trends for 2022” report released by “Xiaohongshu”, in 2021 alone, the reading volume of evaluation notes on the platform exceeded 9 billion times.
Against this backdrop, recombinant collagen products have made a strong breakthrough due to their strong efficacy, and have frequently appeared in the buzzwords of various social platforms, receiving keen attention from consumers.
2、Population Aging
High proportion of elderly population: According to the data of the United Nations Population Division, the global proportion of people aged 65 and above has increased from 6% in 1990 to 10% in 2024, and is expected to continue to grow rapidly.
Long life expectancy per capita: According to the UN 2023, the global average life expectancy has reached 72.6 years.
With the growing trend of an aging population, the healthcare sector is experiencing unprecedented challenges and changes. The growing elderly population is driving overall growth in the fields of orthopedics, cardiovascular diseases, and healthcare. Against this backdrop, the application of recombinant collagen is particularly important, which not only can effectively alleviate skin aging problems, but also plays a key role in a number of fields such as food, medical devices, daily necessities, etc., to maintain the health of consumers in an all-round way.
3、Technological refinement, yield and quality improvement, cost reduction
With the continuous progress of genetic engineering, fermentation process, etc., recombinant collagen technology has been significantly improved, and is now capable of large-scale production, and has successfully reduced the cost of production. This breakthrough has enabled this advanced material to be used in a wider range of applications, thus promoting the development and innovation of related industries.
NIKOO is a high-tech enterprise focusing on the industrialized design and application of biomimetic recombinant functional proteins. With first-class gene recombination, microbial fermentation, protein isolation and purification and other bio-engineering technologies, NIKOO has opened up the large-scale production process of several functional proteins; and realized a full industry chain platform based on recombinant functional proteins from gene design, strain construction, industrialization design, tonnage production capacity scaling up, downstream application research and development, and downstream product safety and efficacy testing. We have realized the whole industry chain platform based on recombinant functional protein from gene design, strain construction, industrialization design, tonnage capacity enlargement, downstream application R&D, downstream product safety and efficacy testing.
4. Perfect policies, research, production and marketing in all fields have laws and regulations
China's emphasis on recombinant collagen has been deepening, and there are relevant laws and regulations on the naming, classification and registration of raw materials, products, etc. These policies and industry norms have provided a good foundation for China's recombinant collagen industry. These policies and industry norms provide a basis and guidance for the research and development and application of recombinant collagen in China, helping China's recombinant collagen to the forefront of the world.
In 2024, the Ministry of Industry and Information Technology and other seven departments issued the “Implementation Opinions on Promoting the Innovative Development of Future Industries”, which puts forward the focus on promoting the development of industries in six major directions: future manufacturing, future information, future materials, future energy, future space and future health. One of the future health direction mentioned, accelerate the cell and gene technology, synthetic biology, biological breeding and other cutting-edge technology industrialization.
5, the market education is perfect, consumer awareness of recombinant collagen egg hundred strengthened
medical beauty market continues to develop: “value economy” prevails, according to the “Tencent 2024 annual light medical beauty consumption trends white paper”, with the education of China's medical beauty market and market regulation continues to optimize, more and more consumers to try light medical beauty more open attitude According to the Tencent 2024 Annual Medical Aesthetics Consumption Trend White Paper, as China's medical aesthetics market continues to optimize education and market regulation, more and more consumers are more open to trying light medical aesthetics, and are showing higher acceptance and willingness to try it out. 72% of the consumers surveyed indicated that they are increasingly accepting of light medical aesthetics-related medical aesthetics. The popularity of the concept of light medical beauty has laid a good foundation for consumers to accept recombinant collagen.
Strong brand marketing: Domestic and foreign brands take recombinant collagen as their core selling point for marketing, and the promotion is strong, which is conducive to increasing consumer recognition and acceptance of recombinant collagen.
Popularization of content: the relevant R & D industry has more recombinant collagen popular science content, to provide consumers with professional and safe advice.
6、Capital injection to accelerate the transformation of results
Although the volatility of the global environment has led to a decline in financing in the field of healthcare in recent years, investment and financing activities in the medical cosmetology industry have remained high. According to data from Artery Intelligence, a total of 30 financings were completed in China's medical aesthetic field in 2024, with a total financing amount of more than RMB 1.1 billion, which is an increase in investment and financing activity compared with 2023.
Specifically, those who obtained financing were mainly upstream enterprises in the medical aesthetics market, and most of these enterprises were concentrated in the injectable filler-related fields.
Since 2024, companies related to advanced materials, including recombinant collagen, hydroxyapatite, filipin, extracellular matrix (ECM), polydeoxyribonucleotide (PDRN), and other advanced materials, have gained access to capital, showing investors' recognition of the future development potential of these innovative technologies and materials.
Third, the future development trend of recombinant Chuan collagen
China's recombinant collagen R & D and application of leading the world, the future will continue to become one of the key players in the global collagen industry.
1, synthetic biology technology to hold the iron amount, recombinant collagen raw material production trip, safety, viscosity, efficacy and so on continue to strengthen
From the laboratory to large-scale production, China's recombinant collagen industrialization development in the world.
2, multi-enterprise entry, raw material end or product end will have more choices, competition intensified
Recombinant collagen's huge market potential has attracted many companies have to devote themselves to it. Polygen Bio, Jinbo Bio, Marimekko Bio, Chuangjian Medical and other companies with early R & D and strategic layout, has achieved a leading position in the industry. Meanwhile, some globalized cosmetic companies also regard recombinant collagen as a new growth point and actively participate in the market competition through acquisitions, mergers & acquisitions, and collaborations.
With the benign development of the industry, it is expected that more advanced products will be launched on the raw material side and the product side, which will bring richer choices to consumers.
3、Enhance its efficacy through multi-product combinations or cross-linking technology, etc.
The complexity of skin structure determines the diversity of its needs. With the unique advantages of recombinant collagen itself, precise formulations and synergistic effects can be realized through clever matching with other ingredients. In addition, through the continuous development of more sophisticated formulation process and cross-linking technology, can further enhance the stability and durability of collagen products, reduce the risk of allergic reactions, while enhancing its filling effect and biocompatibility to meet a wider range of needs.
4, the expansion of application areas, recombinant collagen in the field of medical and medical aesthetic promising
With the development of bioengineering technology, recombinant collagen R & D and production technology is improving, and its significant advantages in terms of safety, purity and bioactivity, is promoting the application of the material in a number of areas of the proportion of the increasing
